Mohammad Raouf Darvich
Department of Chemistry, Faculty of Science, University of Tehran, Tehran, I.R. IRAN
[ 1 ] - Reaction of Sodium Azide with 1,1'–Dicyclohexenyl–Diepoxides
Nucleophilic ring opening of dl and meso 1,1¢- dicyclohexenyl diepoxides by sodium azide in dioxane and aqueous alcoholic medium give the corresponding azidoalcohols. The obtention of departure diepoxides from diazidoalcohols by the reaction with sodium hydride shows the anti position of OH and N3 groups.
[ 2 ] - Effect of Alkyl Substituents on the Hydrogen Catalytic Osmylation of Cis and Trans 2-Cyclohexene-Cyclohexanol
Catalytic osmylation of cis and trans 2-cyclohexene-cyclohexanol (1a) and (1b) are carried out in the presence of N-methyl morpholine-N-oxide. Under the same conditions, only the cis isomer reacted, leading to triol (3). The steric hindrance of the equatorial OH group probably prevents the trans isomer from entering into such reaction. Triol (3) was also obtained from the reduction of the d...
[ 3 ] - Preparation of the Phencyclidine Analogues (Part II)
Using a-tetralone, as starting material, a series of phencyclidine analogues were synthesized. This ketone was reacted separately with ethylmagnesium bromide, P-methoxyphenylmagnesium bromide and P-methylphenylmagnesium bromide. The resultant alcohols were treated with a suspension of NaN3 and CCl3COOH in CHCl3. The azides were subsequently...
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