Mehdi Khoobi
Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran 14176, Iran
[ 1 ] - Magnetic ZnFe2O4 nanoparticles as an efficient catalyst for the oxidation of alcohols to carbonyl compounds in the presence of oxone as an oxidant
Zinc ferrite (ZnFe2O4) nanoparticles were synthesized via the auto-combustion assisted sol-gel method of Zn2+ and Fe3+ ions (molar ratio 1:2) in ammonia solution. The prepared nanomagnetic catalyst was characterized by IR, XRD, SEM and ICP. The diameter of the ZnFe2O4 MNPs (63.7 nm) was determined by Debye-Scherre equation via their XRD pattern. Nanomagnetic ZnFe2O4 efficiently catalyzes oxidat...
[ 2 ] - Aqueous-phase oxidation of alcohols with green oxidants (Oxone and hydrogen peroxide) in the presence of MgFe2O4 magnetic nanoparticles as an efficient and reusable catalyst
Nanomagnetic MgFe2O4 is an active, stable, and reusable catalyst for the oxidation of alcohols. The oxidation of various primary and secondary alcohols has been examined and related corresponding products were obtained in good yields. The reactions were carried out in the presence of water as solvent and oxone (at room temperature) or H2O2 (at 60 ºC) as an oxidant. The catalyst was investigated...
[ 3 ] - Spectroscopic investigation on the interaction of DNA with superparamagnetic iron oxide nanoparticles doped with chromene via dopamine as cross linker
Objective(s): The interaction of DNA with iron oxide nanoparticles (SPIONs) was studied to find out the interaction mechanism and design new drug delivery systems. Materials and Methods: The interaction of calf thymus DNA (ctDNA) with SPIONs doped with 2H-chromene via dopamine as cross linker (SPIONs@DA-Chr) was studied using the UV absorption spectroscopy, viscosity measurement, circular dichr...
[ 4 ] - Cholinesterase Inhibition Activity and Docking Simulation Study of Coumarin Mannich Base Derivatives
Inhibition of acetylcholinesterase and butyrylcholinesterase (AChE and BuChE) as two major forms of cholinesterases (ChEs) is considered as the common approach for the treatment of Alzheimer's disease (AD). The present study was done to explore the anticholinesterase inhibition property of coumarin Mannich base derivatives. A series of cumarin Manich bases were synthesized (4a-h) through one-po...
[ 5 ] - Magnetic ZnFe2O4 nanoparticles as an efficient catalyst for the oxidation of alcohols to carbonyl compounds in the presence of oxone as an oxidant
Zinc ferrite (ZnFe2O4) nanoparticles were synthesized via the auto-combustion assisted sol-gel method of Zn2+ and Fe3+ ions (molar ratio 1:2) in ammonia solution. The prepared nanomagnetic catalyst was characterized by IR, XRD, SEM and ICP. The diameter of the ZnFe2O4 MNPs (63.7 nm) was determined by Debye-Scherre equation via their XRD pattern. Nanomagnetic ZnFe2O4 efficiently catalyzes oxidat...
[ 6 ] - Glucosamine Conjugated Gadolinium (III) Oxide Nanoparticles as a Novel Targeted Contrast Agent for Cancer Diagnosis in MRI
Background: Glucose transporter (Glut), a cellular transmembrane receptor, has a key role in the metabolism of cell glucose and is also associated with various human carcinomas.Objective: In this study, we evaluated a magnetic resonance (MR) imaging contrast agent for tumor detection based on paramagnetic gadolinium oxide (Gd2O3) coated polycyclodextrin (PCD) and mod...
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