Fatemeh Yazdian
Research Center for New Technologies in Life Science Engineering, University of Tehran, Tehran, Iran.
[ 1 ] - Synthesis of the biologically active henna based benzochromene derivatives using ionic liquid functionalized SBA-15 as a nanoreactor
SBA-15 was prepared and then functionalized with N-methyl-N’-propyltrimethoxysilyl imidazolium chloride as ionic liquid moiety. The ionic liquid functionalized SBA-15 (SBA-IL) was characterized by different analytical techniques including FT-IR, N2 adsorption-desorption, TGA and SEM image. According to the obtained results it was found that the organic groups were g...
[ 2 ] - افزایش تولید نایسین در بیوراکتور با کشت همزمان Lactococcus lactis و Yarrowia lipolytica
نایسین اولین نگهدارنده غذایی تایید شده FDA است که در مقیاس صنعتی توسط Lactococcus lactis subsp. lactisتولید میشود. برای کاهش اثر منفی اسید لاکتیک تولید شده در متابولیسم Lactococcus lactis subsp. lactisبر روی تولید نایسین، کشت توام این باکتری با Yarrowia lipolytica استفاده شده است. در این پژوهش برای اولین بارLactococcus lactis به همراه Y. lipolytica در تخمیر بسته با استفاده از بیوراکتور آزمای...
[ 3 ] - تهیه و بررسی اثر ضد میکروبی نانوذرات کامپوزیت پلی ساکاریدی حاوی کارکامین در جلوگیری از تشکیل بیوفیلم میکروبی دندان
Introdution: One of the main reasons of dental caries is the increase in microbial activity in the oral cavity. Streptococcus mutans (S. mutans) is the main etiological agent in dental caries. The aim of this study was preparation and evaluation bio-nanocomposite Chitosan CS-St-MMT encapsulated with Curcumin fabricated by precipitation and ionic gelation method and antimicrobial effect was inve...
[ 4 ] - شبیه سازی دینامیک مولکولی برهمکنش داروی ضد سرطان پاکلیتاکسل با غشای سلولی: بررسی تغییرات انرژی واندروالسی و فاصله مرکز جرم
به دلیل افزایش روزافزون سرطان و تولید داروی جدید در درمان آن در این تحقیق به بررسی برهمکنش داروی جدید ضد سرطان آبگریز پاکلیتاکسل بر روی غشای سلولی با استفاده از ابزارهای محاسباتی پرداخته شده است. از نرم افزار دینامیک مولکولی NAMD و همچنین، نرم افزار VMD برای آماده سازی فایل های ورودی که از بانک داده های پروتیین گرفته شده بودند˛ جهت شبیه سازی و همچنین تحلیل و بررسی داده های خروجی استفاده شده است...
[ 5 ] - Synthesis of the biologically active henna based benzochromene derivatives using ionic liquid functionalized SBA-15 as a nanoreactor
SBA-15 was prepared and then functionalized with N-methyl-N’-propyltrimethoxysilyl imidazolium chloride as ionic liquid moiety. The ionic liquid functionalized SBA-15 (SBA-IL) was characterized by different analytical techniques including FT-IR, N2 adsorption-desorption, TGA and SEM image. According to the obtained results it was found that the organic groups were g...
[ 6 ] - Improvement in curcumin application for preventing dental caries by embeding in nanoparticles
Introdution: The aim of this research was optimization curcumin characteristics for oral hygiene application. Curcumin-loaded starch nano-particles were developed for enhancing adhesion propery with enamel surface and best anti-bacterial effect against Streptococcus mutans. Methods: The study was the experimental one. The nanoparticles synthesize was based on precipitation and ionic gelation m...
[ 7 ] - Anticancer and Apoptotic Effects of Ectoine and Hydroxyectoine on Non-Small Cell Lung Cancer cells: An in-vitro Investigation
Introduction: Streptomyces manage the osmotic stress by collecting compatible solutes or osmolytes. Ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid, and 5-hydroxyectoine are among the most common osmolytes of this bacteria and have an active role in protecting the genetic material of this microorganism as well as providing resistance to environmental pressures. In this researc...
[ 8 ] - Anticancer and Apoptotic Effects of Ectoine and Hydroxyectoine on Non-Small Cell Lung Cancer cells: An in-vitro Investigation
Introduction: Streptomyces manage the osmotic stress by collecting compatible solutes or osmolytes. Ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid, and 5-hydroxyectoine are among the most common osmolytes of this bacteria and have an active role in protecting the genetic material of this microorganism as well as providing resistance to environmental pressures. In this researc...
[ 9 ] - Simulation of Bioreactors for PHB Production from Natural Gas
Recently, many economic studies of poly(3-hydroxybutyrate) PHB production on an industrial scale, and the impact of replacing petrochemical polymers by PHB were carried out, clearly indicating that the most crucial factors to reduce the cost of producing biopolymers are allotted to the application of microbial production strains capable of high productivi...
[ 10 ] - Synthesis and Evaluation of Lipid-based Nanoparticle Containing Ginger Extract against Aspergillus Species
Introduction: Loading the active ingredients of medicinal plants in lipid nanoparticles reduces the reaction of the active substance with the surrounding environment, such as water and oxygen, and reduces the intensity of transmission or evaporation to the external environment. In this study, intended to enhance efficacy of ginger extract, encapsulation in nanoliponiosome synthesized by thin-fi...
[ 11 ] - Investigation of Differentiated Embryonic Stem Cells Growth on Optimized Porous Polymeric Bed with Fuzzy System
Introduction: Age-related macular degeneration (AMD) is one of the retina diseases in which retinal pigment epithelium cells are degraded and lead to blindness. Available treatments only slow down the progression of it. In this study, human embryonic stem cells (hESCs) differentiated into retinal pigment epithelium cells were cultured on a polycaprolactone scaffold. Methods: The optimization o...
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