Saber Yousefi
Department of Clinical Laboratory Sciences, Faculty of Paramedicine, Urmia University of Medical Science
[ 1 ] - Prevalence of PER-1- type Extended-Spectrum Beta-Lactamaes in Clinical Strains of Pseudomonas aeruginosa Isolated from Tabriz, Iran
Objective(s) The aim of this study was to investigate the presence of PER-1-type ESBLs in drug resistant Pseudomonas aeruginosa isolates. Materials and Methods During one-year period (2008-2009), following isolation and identification of 56 P. aeruginosa, the E-test method was performed for determination of minimal inhibitory concentration of ceftazidim. The isolates that they had MIC≥16 µg/ml ...
[ 2 ] - فعالیت ضد‌قارچی اسانس Cinnamomum zeylanicumعلیه جدایه‌های بالینی آسپرژیلوس
مقدمه: آسپرژیلوزیس عفونت قارچی فرصت‌طلبی است که به وسیله گونه‌های مختلف آسپرژیلوس ایجاد می‌شود. تظاهرات بالینی و شدت بیماری بستگی به شرایط فیزیولوژیک بدن میزبان، اندام‌های گرفتار شده و گونه‌های مختلف این قارچ دارد. Cinnamomum zeylanicum یک گیاه همیشه سبز 15 - 10 متری است که به خانواده Lauraceae تعلق دارد و بومی سریلانکا است. اسانس این گیاه دارای خواص ضد‌میکروبی است. هدف: بررسی خواص ضد‌قارچی ...
[ 3 ] - شناسایی مورفولوژیک و مولکولی آسپرژیلوس‌های جداشده از بیماران بر اساس تعیین توالی ژن بتا توبولین (β-tubulin)
Background: Aspergillus species are opportunistic pathogens among immunocompromised patients. In terms of pathogenesis and mycotoxin production, they are in great value. The aim of the this study was to evaluate of beta-tubulin gene for identification of clinical Aspergillus species by PCR-sequencing method compared to morphological features of clinical isolates (such as conidial shape in direc...
[ 4 ] - Candida infections among neutropenic patients
Background: Systemic candidiasis is a major complication in neutropenic cancer patients undergoing treatment. Most systemic fungal infections emerge from endogenous microflora so the aim of the present study was to identify Candida species isolated from the different regions of body in neutropenic patients in compare with the control group. Methods: A total of 309 neutropenic can...
[ 5 ] - Case series of rhinocerebral mucormycosis occurring in diabetic patients
Background: Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%). Case Presentation: In this study, three diabetic patients with rhinocerebral mucormycosis were presented. The etiologic agents of mucormycosis in two patien...
[ 6 ] - Isolation and molecular characterization of Cryptococcus species isolated from pigeon nests and Eucalyptus trees
Background and Purpose: Cryptococcus species are pathogenic and non-pathogenic basidiomycete yeasts that are found widely in the environment. Based on phenotypic methods, this genus has many species; however, its taxonomy is presently being re- evaluated by modern techniques. The Cryptococcus species complex includes two sibling taxa of Cryptococcus neoformans and Cryptococcus gattii. We aimed ...
[ 7 ] - Evaluation of miR-146a expression level in macrophages exposed to Candida glabrata
Background and Purpose: MicroRNAs are small non-coding RNAs with 1924- nucleotides in length. Up- or downregulation of many miRNAs has been shown by stimulation of Toll-like receptors (TLRs) in the innate immune system. Up-regulation of miR-146a has been reported by both TLR and heat-killed Candida albicans. In this study, we aimed to evaluate the expression of miR-146a in cultured monocyte-...
[ 8 ] - Susceptibility pattern of Candida albicans isolated from Iranian patients to antifungal agents
Background and Purpose: Candidiasis is a major fungal infection, and Candida albicans is the major cause of infections in humans. The Clinical and Laboratory Standards Institute (CLSI) developed new breakpoints for antifungal agents against C. albicans. In this multi-center study, we aimed to determine the drug susceptibility profile of C. albicans, isolated from Iranian population according...
[ 9 ] - Interdigital intertrigo due to Fusarium oxysporum
Background and Purpose: Fusariosis is a fungal infection often involving the skin. Various species can cause local, focally invasive, or disseminated infections. The routes of entry for Fusarium species include the respiratory tract, gastrointestinal tract, toe nails, trauma to the skin, and indwelling central venous catheter. Case Report: Herein, we present the case of a 35-year-old woman p...
[ 10 ] - Steroid-binding receptors in fungi: implication for systemic mycoses
It has been shown that some of the mycotic infections especially systemic mycoses show increased male susceptibility and some steroids have been known to influence the immune response. Researchers found that some fungi including yeasts use "message molecules" including hormones to elicit certain responses, especially in the sexual cycle, but until recently no evidence was available to...
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