Leila Hosseinzadeh
School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran
[ 1 ] - Safety Assessment of Ocimum Basilicum Hydroalcoholic Extract in Wistar Rats: Acute and Subchronic Toxicity Studies
Objective(s) Ocimum basilicum L. is widely used in folk medicine of many countries including Iran. Both O. basilicum and its oil extract have received considerable attention for their potential medicinal properties, but there are a few reports about possible toxicity of this plant. Therefore, in the present study, acute and subchronic toxicity of O. basilicum hydroalcohlic extract have been ev...
[ 2 ] - Effect of Curcumin on Doxorubicin-induced Cytotoxicity in H9c2 Cardiomyoblast Cells
Objective(s) Doxorubicin (DOX), a widely used chemotherapeutic agent can give rise to serve cardiotoxicity by inducing apoptosis. Curcumin, the active compound of the rhizome of Curcuma longa L. has anti-inflammatory, antioxidant and anti-proliferative activities. Curcumin has been identified to increase cytotoxicity in several cancer cell lines in combination with DOX, but there is no study a...
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