Koorosh Kamali
Reproductive Biotechnology Research Centre, Avicenna Research Institute (ACECR), Tehran, Iran
[ 1 ] - Ccr2-64i and Ccr5 Δ32 Polymorphisms in Patients with Late-Onset Alzheimer’s disease; A Study from Iran (Ccr2-64i And Ccr5 Δ32 Polymorphisms in Alzheimer’s disease)
Objective(s) Alzheimer’s disease (AD) is a complex disease with multifactorial etiology. Inflammation has been proven to have an important role in the pathogenesis of AD. Both CCR2 and CCR5 genes expression increase in AD patients comparing to control subjects. CCR5 gene encodes a protein which is a member of the beta chemokine receptors family of integral membrane proteins. CCR5-Δ32 is a gene...
[ 2 ] - بررسی ارتباط پلیمورفیسمهای rs1131445 و rs4072111 ژن مسیر التهابی اینترلوکین 16 با بیماری آلزایمر دیررس در ایران
Objectives: Alzheimer’s disease is the most common kind of dementia in the old age, and its incidence increases with age. Previous studies have shown that cytokines are proteins that play an important role in inflammation, and their level changes in inflammatory diseases. Since Alzheimer’s disease is an inflammatory disease, cytokines may influence the occurrence of t...
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