Jalal Izadi Mobarakeh
Department of Pharmacology, Tehran Medical Science Branch, Islamic Azad University, Tehran, Iran
[ 1 ] - Prenatal sex determination in suspicious cases of X-linked recessive diseases by the amelogenin gene
Objective(s):To determine the fetal discernment in suspected cases of sex linked recessive disease in the first trimester of pregnancy. Materials and Methods: After collection of 100 Chorionic Villi samples, the DNAs were extracted and baby gender was determined. Meanwhile, after increasing the sensitivity, the system was able to detect the sex of each cell which was obtained by biopsy. Resul...
[ 2 ] - In-silico Metabolome Target Analysis Towards PanC-based Antimycobacterial Agent Discovery
Mycobacterium tuberculosis, the main cause of tuberculosis (TB), has still remained a global health crisis especially in developing countries. Tuberculosis treatment is a laborious and lengthy process with high risk of non compliance, cytotoxicity adverse events and drug resistance in patient. Recently, there has been an alarming rise of drug resistant in TB. In this regard, it is an unmet need...
[ 3 ] - In-silico Metabolome Target Analysis Towards PanC-based Antimycobacterial Agent Discovery
Mycobacterium tuberculosis, the main cause of tuberculosis (TB), has still remained a global health crisis especially in developing countries. Tuberculosis treatment is a laborious and lengthy process with high risk of non compliance, cytotoxicity adverse events and drug resistance in patient. Recently, there has been an alarming rise of drug resistant in TB. In this regard, it is an unmet need...
[ 4 ] - The Effects of Altered Ultrasound Parameters on the Recovery of Sciatic Nerve Injury
Background: Initial studies have shown that low-energy ultrasound stimulates living tissue cells to reduce regeneration or speed up their recovery. The purpose of this study was to examine the effects of various ultrasound parameters on the speed of recovery in injured sciatic nerves. Methods: NMRI mice (n = 200) with injured left paw, caused by crushing their sciatic nerves, were randomly sel...
[ 5 ] - The Effect of Ultrasound on Acceleration of Peripheral Nerve Injury
Background: Many people suffer from nerve injury. The time consuming nature of the treatments makes the condition worse. Therefore, finding a way to accelerate the process of nerve repair is very important.Objective: To determine the effect of ultrasound on the acceleration of crushed peripheral nerve regeneration.Methods: The experimental model included crushed rat’s sciatic nerve. 40 rats w...