Mehdi Norouzi
Virology Department, Public Health School, Tehran University of Medical Sciences, Tehran, Iran
[ 1 ] - Evaluation of HTLV-1 activity in HAM/TSP patients using proviral load and Tax mRNA expression after In Vitro lymphocyte activation
Objective(s):HTLV-1 is the first human retrovirus that has been recognized and is associated with HAM/TSP and ATLL. Studies have shown that less than five percent of HTLV-1 infected carriers develop HAM/TSP or ATLL and about ninety-five percent remain asymptomatic. Therefore, the proviral load with Tax may affect cellular genes such as cytokines and oncogenes, as well as involve in pathogenicit...
[ 2 ] - Hepatitis B Virus Surface Antigen Variants Clustered Within Immune Epitopes in Chronic Hepatitis B Carriers from Hormozgan Province, South of Iran
Objective(s) The aim of this study was to characterize the hepatitis B virus surface protein genotypes and sequence variations among hepatitis B virus surface antigen (HBsAg) positive chronic patients in Hormozgan province, south of Iran. Materials and Methods A total of 8 patients enrolled in this study. The surface gene was amplified and directly sequenced. Genotypes and nucleotide/amino a...
[ 3 ] - Investigation of the Relationship between HTLV-1 Infection and MMP-3 Gene Expression in HTLV-1 Positive Cardiac Patients
Background and Aims: Human T-lymphotropic virus type 1 (HTLV-1) is a member of retroviridae family that causes ATL and HAM/TSP. Many inflammatory diseases are associated with this virus, such as Sjögren's syndrome, Hashimoto's thyroiditis, Uveitis and also Atherosclerosis. HTLV-1 performs in long latency period and can activate the immune responses in coronary vessels. Activated immune sys...
[ 4 ] - The comparative analysis of the protease molecule structure of the Human lymphotropic virus type-1 (HTLV-1)
Background and Aims: Human lymphotropic virus type-1 (HTLV-1) causes various diseases such as adult T-cell leukemia/lymphoma (ATLL) and HTLV-1 associated myelopathy/tropical spastic paraperesis (HAM / TSP) in humans. The main goal of this study is to compare Iranian protease subtypes structure of this virus (HTLV-1) to samples collected from other part of world in order to understand their diff...
[ 5 ] - Incidence of Hepatitis B virus Surface Antigen (HBsAg) Mutations in Naïve Treated of Chronic Carriers from Tehran Metropolis, Iran
Abstract Background: Naturally occurred hepatitis B virus (HBV) with surface mutations in a variety of chronic hepatitis B (CHB) patients who have received no vaccine or HBIG bearing substitutions in surface protein, have been reported. Objectives: Current knowledge concerning the prevalence of these naturally occurring surface antigen mutations among Iranian carriers is limited. Patients and M...
[ 6 ] - Antimicrobial Effects of SeptiTurbo, Deconex (Solarsept) and 0.525% Sodium Hypochlorite Spray on Alginate Impression Materials
Objectives: Dental impressions are among the potentially infectious items in dentistry. Dental impressions are invariably contaminated with saliva or blood. Such fluids may contain viral or bacterial pathogens including Bacteroides, Fusobacterium, Porphyromonas and Prevotella. The aim of this study was to assess the effects of three different types of disinfectants on alginate impression materi...
[ 7 ] - Evaluation of the effect of Kandovan propolis against Streptococcus Mutans
BACKGROUND AND AIM: In recent years, propolis has been introduced as one the most efficient agents against cariogenic bacteria. However, due to the lack of data on the propolis collected from Kandovan (Easthern Azarbaijan, Iran), this study was designed to investigate the effect of this type of propolis on Streptococcus mutans (S. mutans).METHODS: In this experimental study, the ethanolic extra...
[ 8 ] - Ammonium Chloride as a Potential Candidate for the Treatment and Controlling of Covid-19
Coronaviruses, pathogens with a zoonotic potential, are positive sense single-stranded RNA viruses. SARS Coronavirus-2, the cause of Covid-19 infection, is from the betacoronavirinea subfamily, which has close genomic and proteomic similarity to SARS Coronavirus-1(1). Given the genomic proximity of these two viruses, studies on SARS Coronavirus-1 can be used to control or detect SARS Coronaviru...
[ 9 ] - Antimicrobial Effects of Ethanol and Acetone Extracts of Plantago major Seed on Streptococcus mutans
Background and Aim: This study aimed to compare the effects of acetone and ethanolic extracts of Plantago major (P. major) on S. mutans. Materials and Methods: In this in vitro study, the antibacterial effects of eight different concentrations of the acetone and ethanolic extracts of P. major seed were examined on S. mutans, and the minimum inhibitory concentration (MIC) and minimum bacte...
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