Ladan Teimoori-Toolabi
Molecular Medicine Department, Biotechnology Research Center, Pasteur Institute of Iran
[ 1 ] - A vector-based system for the differentiation of mouse embryonic stem cells toward germ-line cells
Objective(s):To culture thein vitro mouse embryonic stem cells (mESCs) and to direct their differentiation to germ-line cells; in present study we used a vector backbone containing the fusion construct Stra8-EGFP to select differentiated ES cells that entered meiosis. Retinoic acid was used to differentiate embryonic stem cells to germ cells. Materials and Methods: A fragment of Stra8 gene pr...
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