Hossein Eshghi
Department of Chemistry, School of Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
[ 1 ] - Synthesis and docking analysis of new heterocyclic system of tetrazolo[5',1':2,3][1,3,4]thiadiazepino [7,6-b]quinolines as aldose reductase inhibitors
Objective(s):In recent years, the chemistry of Tetrazolo[5',1':2,3][1,3,4]thiadiazepino [7,6-b]quinolines have received considerable attention owing to their synthetic and effective biological importance which exhibits a wide variety of biological activity. As the inhibitor of aldose reductase, the aforementioned compounds may have implication in preventing complications of diabetes. Materials...
[ 2 ] - Gold-gold sulfide nanoshell as a novel intensifier for anti-tumor effects of radiofrequency fields
Objective(s):Several studies have been carried out to investigate the effect of various nanoparticles exposed to radiofrequency (RF) waves on cancerous tissues. In this study, a colon carcinoma tumor model was irradiated by RF in the presence of gold-gold sulfide (GGS) nanoshells. Materials and Methods: Synthesis and characterization of GGS nanoshells were initially performed. CT26 cells were ...
[ 3 ] - Sonodynamic Therapy Using Protoporphyrin IX Conjugated to Gold Nanoparticles: An In Vivo Study on a Colon Tumor Model
Objective(s) Sonodynamic therapy is a physical treatment which utilizes ultrasound waves with an appropriate sensitizer such as protoporphyrin IX (PpIX). The activation of sensitizer depends on cavitation, and therefore, high intensity ultrasound is an important necessity. Beside, high intensity ultrasound can induce side effects on the healthy tissues which have surrounded tumor. The particle...
[ 4 ] - Preconcentration and Determination of Lead for Trace Levels in Water and Wastewater Samples by Vortex-Assisted Microextraction Using TPAS as a New Synthetic Complexing Agent with Electrothermal Atomic Absorption Spectroscopy Detection
A simple and rapid solidified vortex assisted 1-undecanol based liquid-liquid microextraction technique was proposed for preconcentration of trace levels of lead ions. The extraction solvent (1-undecanol) was dispersed into the aqueous samples by the assistance of vortex agitator. 100 µL of 1-undecanol containing ethyl (2Z)-3-[(5-chloro-7-methyl[1,3]thiazolo[5,4-d]pyrimidi...
[ 5 ] - A Novel Carbon Paste Electrode for Potentiometric Determination of Vanadyl Ion
Carbon paste electrode was modified by disodium 2,4-diamino-7-methylbenzo[g] pteridine-5,10-dioxide to fabricate a sensor for potentiometric determination of vanadyl ion (VO2+) in aqueous medium. The new ligand was synthesized in three steps with high yield. The optimal composition of the carbon paste was made of graphite powder (64.5%), ionophore (16.6%), paraffin oil (17.8%), a...
[ 6 ] - A Novel and Efficient Synthesis of New Dixanthones
The facile and high yield synthesis of a new series of dibenzophenones in the presence of polyphosphoric acid (PPA) together with their cyclization to corresponding moni and dixanthones are described. The aromatic nucleophilic substitution of these new compounds are also studied.
[ 7 ] - Induction of Localized Hyperthermia by Millisecond Laser Pulses in the Presence of Gold-Gold Sulphide Nanoparticles in a Phantom
Introduction Application of near-infrared absorbing nanostructures can induce hyperthermia, in addition to providing more efficient photothermal effects. Gold-gold sulfide (GGS) is considered as one of these nanostructures. This study was performed on a tissue-equivalent optical-thermal phantom to determine the temperature profile in the presence and absence of GGS and millisecond pulses of a ...