Saeed Azizi
Department of Clinical Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
[ 1 ] - Alpha-lipoic acid loaded in chitosan conduit enhances sciatic nerve regeneration in rat
Objective(s): To investigate the effect of topical administration of alpha-lipoic acid into chitosan conduit on peripheral nerve regeneration using a rat sciatic nerve transection model. Materials and Methods: Forty five Wistar rats were divided into three experimental groups randomly. A 10-mm gap of sciatic nerve was bridged with a chitosan conduit following surgical preparation and anesthesia...
[ 2 ] - The effect of ubiquinone on functional recovery and morphometric indices of sciatic nerve regeneration
A common cause of peripheral nerve injury is trauma. The positive effect of antioxidants on the improvement of nerve regeneration has currently become a focus of attention. In this experiment, the effect of intraperitoneal administration of ubiquinone (CoQ10) on an acute experimentally sciatic nerve crush was studied in a rat model. Forty-five male Wistar rats, weighing between 160-180 g were u...
[ 3 ] - The healing effect of chitosan supported nano-CeO2 on experimental excisional wound infected with pseudomonas aeruginosa in rat
Objective- The healing effect of chitosan supported cerium oxide nanoparticles (nano-CeO2) on cutaneous experimental excisional wound infected with pseudomonas aeruginosa was studied in rat. Design- Experimental Study. Animals- Sixty male albino rats. Procedures- The chitosan supported nano-CeO2 hydrogel was prepared and characterized using Fourier-transform infrared spectro...
[ 4 ] - The Long-term Effects of Uncultured Omental Adipose-derived Nucleated Cells Fraction and Bone-marrow Stromal Cells on Sciatic Nerve Regeneration
Objective- Adipose tissue is an appropriate source for isolation of cells with stem-cell–like properties. In the present long-term study, the effects of the omental adipose-derived nucleated cells (OADNCs) fraction were compared to those of the undifferentiated cultured bone marrow stromal cells (BMSCs) on sciatic nerve regeneration. Design- Experimental in vivo study. Animals- Fift...
[ 5 ] - Use of Chitosan Conduit for Bridging Small-Gap Peripheral Nerve Defect in Sciatic Nerve Transection Model of Rat
Objective-To evaluate effect of chitosan conduit for peripheral nerve regeneration using sciatic nerve transection model in rat Design- Experimental in vivo study. Animals- Sixty healthy male Wistar rats. Procedures-The rats were divided into four experimental groups (n=15) randomly. In sham group the left sciatic nerve was exposed through a gluteal muscle incision and after careful...
[ 6 ] - Functional, Histomorphometrical and Immunohistochemical Assessment of Sciatic Nerve Regeneration through Inside-Out Vein Graft in Rat
Objective- Comprehensive functional, histomorphometrical and immunohistochemical assessment of sciatic nerve regeneration through an inside-out vein graft in rat. Design- Experimental in vivo study. Animals- Fifty- four healthy male White Albino rats. Procedures- The rats were divided into three experimental groups (n=18), randomly: Sham-operation (NC), Transected control (TC) and Inside-out ve...