Masoud Karimi-Googheri
Department of Immunology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran
[ 1 ] - The frequency of CCR5 promoter polymorphisms and CCR5 32 mutation in Iranian populations
Evidence showed that chemokines serve as pro-migratory factors for immune cells. CCL3, CCL4 and CCL5, as the main CC chemokines subfamily members, activate immune cells through binding to CC chemokine receptor 5 or CCR5. Macrophages, NK cells and T lymphocytes express CCR5 and thus, affected CCR5 expression or functions could be associated with altered immune responses. Deletion of 32 base pai...
[ 2 ] - The effect of depression and anxiety on expression levels of toll like receptor signaling moleculesin chronic HBV infected patients
Background: Toll- like receptors (TLRs) play an important role in the recognition of DAMPs and PAMPs and induction ofinflammation. Previous studies demonstrated that depression and anxiety can influence the expression levels of immune related molecules. Our previous study revealed that mRNA levels of IRAK4, TRAF3 and IRF7 were significantly decreased in chronic HBV infected (CHB) patients whe...