Abdolaziz Rastegar Lari
Department of Microbiology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
[ 1 ] - Association between mutations in gyrA and parC genes of Acinetobacter baumannii clinical isolates and ciprofloxacin resistance
Objective(s): We investigated the contribution of gyrA and parC mutational mechanism in decreased ciprofloxacin susceptibility of Acinetobacter baumannii isolated from burn wound infections. Materials and Methods: Ciprofloxacin susceptibility of 50 A. baumannii isolates was evaluated by disk diffusion and agar dilution methods. PCR and sequencing were performed for detection of mutation in gyr...
[ 2 ] - Investigation of Efflux-Mediated Tetracycline Resistance in Shigella Isolates Using the Inhibitor and Real Time Polymerase Chain Reaction Method
Background: Shigella spp. are gram negative bacteria, which are of global public health importance. The growing of multidrug-resistant Shigella isolates are a major problemaround the world. Methods: Overall, 50 isolates of Shigella spp. from children diarrheic stools w...
[ 3 ] - Characterization of Carbapenemases in Extensively Drug Resistance Acinetobacter baumannii in a Burn Care Center in Iran
The emergence of multidrug resistance (MDR) and extensively drug resistance (XDR) in Acinetobacter baumannii has made an important challenge in the treatment of infections caused by this organism. The ability of carbapenemase production is one of the main mechanisms for the emergence of MDR and/or XDR in A. baumannii. The aim of this study was to detect carbapenemase producer A. baumannii. In t...
[ 4 ] - بررسی خاصیت تهاجمی سلولی سروتیپ های شیگلا جدا شده از بیماران مبتلا به اسهال در کشت سلولی HEp-2
زمینه و هدف: اسهال یکی از مهمترین علل مرگ و میر کودکان در کشورهای در حال توسعه است. بیماری های روده ای سالانه سبب مرگ بسیاری از کودکان زیر 5 سال می گردند. یکی از روش هایی که امکان بررسی خاصیت تهاجمی باکتری ها را می دهد، استفاده از کشت سلول است. هدف از این مطالعه بررسی خاصیت تهاجمی تعدادی از سویه های جنس شیگلا با استفاده از کشت سلولی HEp-2 بوده است. روش بررسی: در این مطالعه توصیفی تحلیلی، سوآپ...