Iraj Salehi
Chronic Diseases (Home Care) Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
[ 1 ] - Resveratrol attenuates visfatin and vaspin genes expression in adipose tissue of rats with type 2 diabetes
Objective(s): Visfatin and vaspin are secreted by adipose tissue and play key roles in glucose homeostasis and subsequently are potential targets for diabetes treatment. Resveratrol (RVS) corrects insulin secretion and improves insulin sensitivity. We investigated the RVS effects on serum antioxidants, insulin and glucose levels, also visfatin and vaspin genes expression in adipose tissue of st...
[ 2 ] - Wrestlers’ immune cells produce higher interleukin-6 and lower interleukin-12 and interleukin-13 in response toin vitro mitogen activation
Objective(s):Although recent investigations have shown chronic inflammation and inflammation-associated diseases might be ameliorated by exercise; little is known about the relation between exercise training with anti/pro-inflammatory cytokines. Materials and Methods: This cross sectional study was conducted to compare interleukin-4 (IL-4), IL-6, IL-10, IL-12, IL-13, interferon gamma (IFN-γ) le...
[ 3 ] - Amlodipine Ameliorates Up-Regulation of ET-1 in Left Ventricle of Hypercholesterolemia Rabbits
Objective(s) In addition to antihypertensive effects, amlodipine may exhibit cardiovascular protective effects in heart tissue. The aim of this study was to evaluate the effects of amlodipine and/or high cholesterol diet on blood, heart tissue concentration and mRNA expression of endothelin-1 (ET-1) in male New Zealand white rabbits. Materials and Methods A total of 40 male New Zealand rabbi...
[ 4 ] - The Pattern of Brain-Derived Neurotrophic Factor Gene Expression in the Hippocampus of Diabetic Rats
Objective(s) The aim of this study was to evaluate the effects of regular exercise in preventing diabetes complication in the hippocampus of streptozotocin (STZ)-induced diabetic rat. Materials and Methods A total of 48 male wistar rats were divided into four groups (control, control exercise, diabetic and diabetic exercise). Diabetes was induced by injection of single dose of STZ. Exercise ...
[ 5 ] - اثرات مصرف عصاره هیدروالکلی مقل ازرق بر آنزیم‌های قلبی، پروفایل لیپیدی و گلوکز خون در موش‌های صحرایی دیابتی
Introduction: Diabetes mellitus is the most common non-communicable diseases in the world which has affected more than 3 million people in Iran. Since ancient time, herbs were used in the treatment of diabetes. Hence, this study intends to investigate the effect of Hydro Alcoholic Extract of Commiphora Mukul on cardiac enzymes, lipid profile and blood glucose in diabetic male rats. Methods: I...
[ 6 ] - تاثیر ورزش اجباری تردمیل بر وضعیت استرس اکسیداتیو در قلب رت‌های دیابتیک
Introduction & Objective: Diabetes is a metabolic disorder caused by low secretion or resistance to the insulin action. Oxidative stress, as a result of imbalance between the free radical production and antioxidant defense systems is strongly related to diabetes and its complications. The aim of the present study is to evaluate the effect of experimental diabetes and forced treadmill exercise...
[ 7 ] - تاثیر پرفشاری خون مدل رنوواسکولار بر اسپرماتوژنز در موش صحرایی
Introduction & Objective: Change in function of general and regional rennin- angiotensin system is the most important factor in cardiovascular disorders and essential hypertension. Recent studies show that general rennin- angiotensin system influence immediate and short term responses and tissue or regional rennin- angiotensin system influence long term process in control of heart and vascula...
[ 8 ] - تاثیر ورزش شنا بر استرس اکسیداتیو و شاخص آتروژنیک در خون رت‌های نر دیابتیک
Background & Objective: Diabetes is a metabolic disorder caused by low secretion or resistant to the insulin action. Oxidative stress, an imbalance between the free radical production and antioxidant defense systems of the body, is strongly related to diabetes and its symptoms. The aim of the present study is to evaluate effect of regular swimming on antioxidant system in diabetes. Materia...
[ 9 ] - Vitamin C Can Alter Lead-Induced Passive Avoidance Learning Impairment in Rats
Introduction: Lead (Pb) is a neurotoxin that its different effects on the central nervous system are well-known. Previous studies have reported the potent effects of vitamin C on memory.The present study was undertaken to evaluate the protective effects of vitamin C against leadinduced amnesia. Methods: Male Wistar rats were divided into 4 groups: the control (saline), negative contr...
[ 10 ] - Interaction Between the Cannabinoid and Vanilloid Systems on Anxiety in Male Rats
Introduction: Previous studies have shown that the cannabinoid system is involved in anxiety.In addition, transient receptor potential vanilloid type-1 (TRPV1) channels are new targets for the development of anxiolytics. The present study investigated the possible interaction between the cannabinoid and vanilloid systems on anxiety-like behavior in rats. Methods: Four different groups of male ...
[ 11 ] - Preconditioning Effect of High-Intensity Aerobic Training on Myocardial Ischemia-Reperfusion Injury and Beclin-1 Gene Expression in Rats
Purpose: Ischemia-Reperfusion (IR) injury is one of the most common cardiac disorders leading to irreversible heart damage. Many underlying mechanisms seem to be involved, among which disruption of cellular autophagy balance. Since physical training has a beneficial effect on the improvement of autophagy balance, it may have a cardioprotective effect against IR injury. This study investigates t...
[ 12 ] - Comparing the Impact of Long-Term Exposure to Extremely Low-Frequency Electromagnetic Fields With Diverse Values on Anxiety, Memory, Learning, and Β-Amyloid Deposition in Adult Rats
Background: Extremely low-frequency electromagnetic fields (ELF-EMFs) have gathered significant consideration for their possible pathogenicity. However, their effects on nervous system functions were not fully clarified. In this study, our aim was to assay the effect of ELF-EMFs with different intensity on memory, anxiety, antioxidant activity, beta amyloid (Aβ) deposition and microglia populat...
[ 13 ] - Risk assessment of nurse anesthetist job using hybrid AHP-CoCoSo
Background and purpose:Anesthesiology experts are exposed to significant risks due to advancements in anesthesia techniques and surgery, as well as the emergence of modern equipment and newer drugs, along with increased responsibilities and expectations. Therefore, the present study was conducted with the aim of providing a model for assessing the risks and hazards existing in this profession. ...
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