Mahdi Abastabar
Invasive Fungi Research Center, Department of Medical Mycology and Parasitology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
[ 1 ] - Down-regulation of miR-135b in colon adenocarcinoma induced by a TGF-β receptor I kinase inhibitor (SD-208)
Objective(s):Transforming growth factor-β(TGF-β) is involved in colorectal cancer (CRC). The SD-208 acts as an anti-cancer agent in different malignancies via TGF-β signaling. This work aims to show the effect of manipulation of TGF-β signaling on some miRNAs implicated in CRC. Materials and Methods: We investigated the effects of SD-208 on SW-48, a colon adenocarcinoma cell line. The cell li...
[ 2 ] - تعیین فراوانی کلنیزاسیون پنوموسیستیس جیرووسی در نمونه های تنفسی مبتلایان به نارسایی ریوی با روش های میکروسکوپی
Background and purpose: Respiratory failures are common diseases among different populations. Pneumocystis jirovecii colonization causes respiratory failure in children and adults with AIDS and patients with predisposing factors of immunosuppression including malignancies, organ transplant, inherited immune deficiencies and immunosuppressive agents. The aim of this study was to evaluate the eff...
[ 3 ] - In vitro antitumor activity of patulin on cervical and colorectal cancer cell lines
Background and Purpose: Patulin is a mycotoxin produced by some molds,especially Aspergillus and Penicilium, and is responsible for mycotoxicosis in animals and humans.There is still not very detailed data about the anti-cancer potency of patulin, but some reports demonstrated that it induces cellular apoptosis and toxicity. Materials and Methods: To determine the efficacy of patulin as a ther...
[ 4 ] - Hyphal wall protein 1 gene: A potential marker for the identification of different Candida species and phylogenetic analysis
Background and Purpose: Hyphal wall protein 1 (HWP1) is an important adhesin which usually is expressed on the germ tube and hyphal surface produced by different Candida species. The hyphal wall protein-coding gene (HWP1) was evaluated as a novel identification and phylogenetic marker in Candida tropicalis, C. orthopsilosis, C. parapsilosis and C. glabrata. Materials and Methods: Initially, fo...
[ 5 ] - Molecular Identification and Epidemiological Aspects of Dermatophytosis in Tehran, Iran
Background: Dermatophytes are the most common fungal agents causing superficial skin infections in worldwide. Species identification of these fungi is important for therapeutic and epidemiological apects. The purpose of this study was identification and epidemiology of dermatophytosis in patients referring to medical mycology laboratory of Razi hospital in Tehran, during 2014. Materials and Me...
[ 6 ] - Prevalence of specific immunoglobulin E and G against Aspergillus fumigatus in patients with asthma
Background and Purpose: Aspergillus fumigatus as a ubiquitous fungus can be found in the respiratory tract of the asthmatic and healthy people. The inhalation of Aspergillus spores leads to an immune response in individuals with asthma and results in the aggravation of the clinical symptoms. The present study aimed to investigate the prevalence of specific immunoglobulin E and G (IgE and IgG) a...
[ 7 ] - Effects of Acetic Acid Vaginal Gel on Vulvovaginal Candidiasis: A Double Blind Randomized Controlled Trial
Background and purpose: It is estimated that 70–75% of women experience one episode of vulvovaginal candidiasis (VVC) during childbearing age and 40-50% suffer from recurrent VVC. Because of the resistance of Candida species to certain drugs, such as azoles, physicians tend to use complementary or alternative medicine such as vinegar in treatment of VVC. The current study aimed to determine the...
[ 8 ] - Mucormycosis: A Lethal Phenomenon in COVID-19 Patients: A Review of Diagnostic and Therapeutic Approaches
Coronavirus disease 2019 (COVID-19) has seriously spread worldwide. One of the problems of COVID-19 patients is co-infection with other microbial infections such as fungal infections that are severely life-threatening. Mucormycosis, one of these opportunistic fungal diseases that is mistakenly known as black fungal disease, has been reported in Iran and the world. This non-systematic review is ...
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