Narguess Yassa
Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran
[ 1 ] - Essential oils chemical composition, antioxidant activities and total phenols of Astrodaucus persicus
Objective(s):Astrodaucus persicus, Apiaceae, is used as vegetable or food additive in some parts of Iran. The essential oils of different parts of Astrodaucus persicus from Kordestan province were analyzed for the first time and compared with other regions. In this study, antioxidant activities and total phenols determination of aerial parts essential oils and root fractions of A. persicus were...
[ 2 ] - Crude Methanol Extract of Echinophora Platyloba Induces Apoptosis and Cell Cycle Arrest at S-Phase in Human Breast Cancer Cells
The aim of the present study was to determine cytotoxic activity of crude methanolicextract of Echinophora platyloba on breast cancer MDA-MB-231 cell line. The free radicalscavenging effects of methanolic extract of E. platyloba were tested using DPPH method.Crude methanolic extract exhibited potential antioxidant activity with an IC50 value of 234.28 ±21.63 μg/mL when compared to the standard ...
[ 3 ] - Isolation of Phenolic Derivatives and Essential Oil Analysis of Prangos ferulacea (L.) Lindl. Aerial Parts
Prangos ferulacea (L.) Lindl. (Apiaceae) is a medicinal plant distributed in Mediterranean regions, Caucasia and southwest of Asia. In the present study phytochemical constituents of the extract obtained from the aerial parts of P. ferulacea were investigated using various chromatographic and spectroscopic methods. Essential oil of the plant aerial parts was also analyzed using GC-MS. Five phen...
[ 4 ] - Phytochemical and Antioxidant Investigation of the Aerial Parts of Dorema glabrum Fisch. & C. A. Mey
Dorema glabrum Fisch. & C.A. Mey. (Apiaceae) is a monocarpic perennial plant distributed in southern Caucasus. In Azerbaijan Republic folk medicine, the gum-resin of this species is used as a diuretic and anti-diarrheal agent. It is also traditionally used for the treatment of bronchitis and catarrh. In the present study, chemical constituents of the essential oil and extract of D. glabrum aeri...
[ 5 ] - Antimicrobial Activities of Three Medicinal Plants and Investigation of Flavonoids of Tripleurospermum disciforme
Rosa damascena, Tripleurospermum disciforme and Securigera securidaca were used as disinfectant agents and for treatment of some disease in folk medicine of Iran. The antimicrobial effects of different fractions of seeds extract of S. securidaca, petals extract of R. damascena and aerial parts extract of T. disciforme were examined against some gram positive, gram negative and fungi by cup plat...
[ 6 ] - Crude Methanol Extract of Echinophora Platyloba Induces Apoptosis and Cell Cycle Arrest at S-Phase in Human Breast Cancer Cells
The aim of the present study was to determine cytotoxic activity of crude methanolicextract of Echinophora platyloba on breast cancer MDA-MB-231 cell line. The free radicalscavenging effects of methanolic extract of E. platyloba were tested using DPPH method.Crude methanolic extract exhibited potential antioxidant activity with an IC50 value of 234.28 ±21.63 μg/mL when compared to the standard ...
[ 7 ] - Isolation of Phenolic Derivatives and Essential Oil Analysis of Prangos ferulacea (L.) Lindl. Aerial Parts
Prangos ferulacea (L.) Lindl. (Apiaceae) is a medicinal plant distributed in Mediterranean regions, Caucasia and southwest of Asia. In the present study phytochemical constituents of the extract obtained from the aerial parts of P. ferulacea were investigated using various chromatographic and spectroscopic methods. Essential oil of the plant aerial parts was also analyzed using GC-MS. Five phen...
[ 8 ] - Phytochemical and Antioxidant Investigation of the Aerial Parts of Dorema glabrum Fisch. & C. A. Mey
Dorema glabrum Fisch. & C.A. Mey. (Apiaceae) is a monocarpic perennial plant distributed in southern Caucasus. In Azerbaijan Republic folk medicine, the gum-resin of this species is used as a diuretic and anti-diarrheal agent. It is also traditionally used for the treatment of bronchitis and catarrh. In the present study, chemical constituents of the essential oil and extract of D. glabrum aeri...
[ 9 ] - Antimicrobial Activities of Three Medicinal Plants and Investigation of Flavonoids of Tripleurospermum disciforme
Rosa damascena, Tripleurospermum disciforme and Securigera securidaca were used as disinfectant agents and for treatment of some disease in folk medicine of Iran. The antimicrobial effects of different fractions of seeds extract of S. securidaca, petals extract of R. damascena and aerial parts extract of T. disciforme were examined against some gram positive, gram negative and fungi by cup plat...
[ 10 ] - بررسی اثرات ضدباکتریایی گیاه Scrophularia striata Boiss. بر روی سویه‌های مقاوم Pseudomonas aeruginosa
مقدمه: گیاه Scrophularia striata یا تشنه‌داری در زبان محلی، از خانواده گل میمون (Scrophulariaceae) است که در استان ایلام برای رفع عفونت‌های ادراری و عفونت‌های بانوان مصرف می‌شود. هدف: تأثیر عصاره و فراکشن‌های قسمت‌های هوایی گیاه بر روی 50 سویه مقاوم باکتری Pseudomonas aeruginosa مورد بررسی قرار گرفت تا اثر مناسب‌ترین بخش عصاره و میزان اثر آن بر روی این باکتری که یکی از عوامل مؤثر در عفونت‌های ا...
[ 11 ] - شناسایی ترکیبات روغن فرار گیاه Zeravschania membranacea و مقایسه آن با اسانس گیاه Z. pastinacifolia
مقدمه: اسانس‌ها مواد طبیعی موجود در گیاهان هستند که مواد تشکیل‌دهنده آنها به عواملی چون ژنتیک، آب و هوا و زیستگاه و غیره وابستگی دارد. گیاهان خانواده چتریان از نظر وجود اسانس غنی می‌باشند که به دلیل تنوع و تفاوت اثرات خود در پزشکی سنتی و جدید مصرف دارند. هدف: مقایسه اسانس دو گیاه بومی ایران از جنس Zeravschania می‌باشد. روش تحقیق: گیاهZeravschania membranacea (Boiss.) M. Pimenov در تیرماه سال...
[ 12 ] - بررسی اجزای تشکیل‌دهنده و اثرات ضدمیکروبی اسانس حاصل از برگ گیاه Peucedanum ruthenicum (M. Bieb.) Rochel جمع‌آوری شده از کلاردشت
مقدمه: در طول تاریخ بشریت بسیاری از بیماری‌های عفونی با گیاهان دارویی درمان شده‌اند به طوری‌که امروزه در بسیاری از کشورهای در حال توسعه داروهای گیاهی نقش اصلی را در درمان‌های اولیه ایفا می‌کنند و در بسیاری از کشورها گیاهان به عنوان منبع منحصر به فردی در تهیه داروها محسوب می‌شوند. هدف: تجزیه و شناسایی مواد موجود در اسانس و بررسی اثرات ضدمیکروبی آن، که در صورت داشتن اثرات مطلوب بعد از بررسی‌ه...
[ 13 ] - Chemical Constituents and Antibacterial Activity of Essential Oil of Peucedanum ruthenicum M. Bieb. Fruits
The essential oil of Peucedanum ru t h e n i c u m fruits, obtained by hydrodistillation, was analyzed by gas chromatography and gas chromatography mass spectrometry. Among the 31 identified constituents accounting for 83.9% of the total oil, the major components were 1,8-cineole (11.15%), camphor (5.86%), Z-carveol (6.88%), l-carvone (5.61%), 8,9-dehydroisolongifolene (1...
[ 14 ] - Phytochemical Evaluation, Antioxidant Activity and Toxicity of Paeonia daurica ssp. macrophylla Root
Background and objectives: Paeonia daurica ssp. macrophylla, is an herbaceous and perennial plant which belongs to Paeoniaceae family. Two species of this plant grow in northern parts of Iran. The roots in powder form have been used in Persian traditional medicine for treatment of epilepsy, nightmares and gynecological diseases. Several biological activities s...
[ 15 ] - Biological Evaluation of the Isolated Compounds from Methanol fraction of Leutea avicennia Mozaff.
Leutea avicenniae Mozaff. belongs to Apiaceae family is an endemic species distributed in the west of Iran. The aim of this study was to investigate the antioxidant activity and acetylcholinestrase (AchE) inhibition of the crude extract, fractions and isolated compounds from methanolic fraction of L. avicenniae. Five compounds were detected from methanol fraction, three phenolic compounds as p-...
[ 16 ] - Biological Evaluation of the Isolated Compounds from Methanol fraction of Leutea avicennia Mozaff.
Leutea avicenniae Mozaff. belongs to Apiaceae family is an endemic species distributed in the west of Iran. The aim of this study was to investigate the antioxidant activity and acetylcholinestrase (AchE) inhibition of the crude extract, fractions and isolated compounds from methanolic fraction of L. avicenniae. Five compounds were detected from methanol fraction, three phenolic compounds as p-...
[ 17 ] - Chemical Composition and Biological Activity of Ferula aucheri Essential Oil
Background and objectives: Antibiotics resistance and unpleasant side effects of AChE inhibitors have led to an increased interest in herbs as potential sources. Ferula aucheri (Syn: Dorema aucheri) an indigenous species of Ferula (Apiaceae) grows in Iran and is used as food and medicinal plant. The present study was aimed to identify the oil composit...
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