Seyed Hamid Madani
Department of Pathology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
[ 1 ] - Protective effect of crocin on gentamicin-induced nephrotoxicity in rats
Objective(s): Gentamicin is used for the treatment of Gram-negative bacterial infections. However, gentamicin administration is limited because of nephrotoxicity. The aim of the present study was to evaluate the protective effect of crocin against gentamicin-induced nephrotoxicity in rats. Materials and Methods: Thirty two male Wistar rats received gentamicin (100 mg/kg, IP), with or without c...
[ 2 ] - Kaposifrom Hemangioendothelioma of the Skull in a 3 Year--Old Boy
Kaposiform hemangioendothelioma (KHE) appears as a single lesion at birth or early infancy in an equal sex ratio. A rare aggressive vascular proliferation has been recognized as a separate entity from other childhood vascular neoplasm. A 3-year-old Iranian boy with a rapidly enlarging mass in his (posterior aspect of skull at the midline) skull was present here. Physical examination revealed...
[ 4 ] - Protective Effect of P-Coumaric Acid against Cisplatin-Induced Nephrotoxicity and Hepatotoxicity in Rats
Background and purpose: Cisplatin is used in chemotherapy for cancer patients. But, it has adverse effects on some organs, including the kidney and liver. P-coumaric acid is a polyphenolic substance with multiple biological properties. The present study aimed to investigate the effect of p-coumaric acid on renal and hepatic side effects of cisplatin. Materials and methods: This experimental st...
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