Mehran Mesgari Abbasi
Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran|Students Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
[ 1 ] - Inhibitory effect of clemastine on P-glycoprotein expression and function: an in vitro and in situ study
Objective(s):Transporters have an important role in pharmacokinetics of drugs. Inhibition or induction of drug transporters activity can affect drug absorption, safety, and efficacy. P-glycoprotein (P-gp) is the most important membrane transporter that is responsible for active efflux of drugs. It is important to understand which drugs are substrates, inhibitors, or inducers of P-gp to minimize...
[ 2 ] - تأثیر مصرف زردچوبه بر سطوح سرمی مولکول اتصالی داخل سلولی، آهن، فریتین و ظرفیت کلی اتصال به آهن در افراد مبتلا به کبد چرب غیرالکلی
مقدمه: مطالعه حاضر با هدف بررسی تأثیر مصرف زردچوبه بر سطوح سرمی مولکول اتصالی داخل سلولی (ICAM)، آهن، فریتین و ظرفیت کلی اتصال به آهن (TIBC) به عنوان بخشی از عوامل خطر قلبی ـ عروقی در افراد مبتلا به کبد چرب غیرالکلی (NAFLD) انجام شد. مواد و روش‌ها: کارآزمایی بالینی تصادفی دو سوکور کنترلدار حاضر بر روی 46 فرد مبتلا به NAFLD مراجعه‌کننده به پزشک متخصص گوارش و تشخیص داده شده به روش سونوگرافی کبد،...
[ 3 ] - Effects of conjugated linoleic acid supplementation on serum levels of interleukin-6 and sirtuin 1 in COPD patients
Objective: Chronic obstructive pulmonary disease (COPD) is characterized by systemic inflammation and accelerated inflammaging of the lungs. Some studies showed that conjugated linoleic acid (CLA) has anti-inflammatory effects. The aim of the present study was to evaluate the effect of CLA supplementationon serum levels of interleukin (IL)-6 and sirtuin1 (SIRT1) in patients wit...
Co-Authors