Gokhan Pusuroglu
Recep Tayyip Erdogan University, School of Medicine, Department of Internal Medicine, Rize, Turkey
[ 1 ] - The protective effect of infliximab against carbon tetrachloride-induced acute lung injury
Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-α). We aimed to investigate whether Ib has a protective effect on CCl4 induced lung injury. Materials and Methods:Rats were divided into control, CCl4, and CCl4+Ib groups. A single dose of 2 ml/kg CCI4 was administered to CCI4 group and a single dose of...
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