Marzyeh Kamyar

School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

[ 1 ] - Crocin prevents haloperidol-induced orofacial dyskinesia: possible an antioxidant mechanism

Objective(s):Long-term treatment with antipsychotics causes serious side effects such as tardive dyskinesia that characterized by abnormal movements in the orofacial region. Oxidative stress in the brain specific area is implicated in the pathophysiology of tardive dyskinesia. In this study the protective effect of crocin on haloperidol-induced orofacial dyskinesia was evaluated. Materials and ...