Mohammad Afshar
Department of Anatomy, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran|Medical Toxicology Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran
[ 1 ] - A novel atheroprotective role of MF59-like adjuvant when co-administered with CETP vaccine in rabbit model of atherosclerosis
Objective(s): In this study, for the first time, MF59 adjuvant was used to develop a cholesteryl ester transfer protein (CETP) vaccine. The efficacy of the vaccine was compared with the efficacy of CETP vaccine formulated with Alum/CpG, the formulation that its immunogenicity has been already demonstrated in rabbit and mice. Materials and Methods: Tetanus toxoid- CETP peptide (TT-CETP) was mixe...
[ 2 ] - Evaluation of cutaneous wound healing activity of Malva sylvestris aqueous extract in BALB/c mice
Objective(s): The aim of this study was to evaluate the effects of Malva sylvestris aqueous extract on cutaneous wound healing in BALB/c mice. Materials and Methods: Twenty seven male BALB/c mice (2.5 months of age) were used. A cut wound (superficial fascia depth) was made locally. The mice were then divided into three groups: the first, second and third groups received topical administration ...
[ 3 ] - Preventive Effect of Vitamin B6 on Developmental Toxicity of Carbamazepine in Mice
Objective(s) Carbamazepine (CBZ) is an antiepileptic drug that is used widely for the treatment of epileptic seizures. Neural tube defects (NTDs), growth retardation, and nail hypoplasia are the most common features of teratogenic effects of this drug. The purpose of this study was to examine the effect of vitamin B6 on the developmental toxicity of CBZ on mice. Materials and Methods Sixty B...