Mohammad Moshiri
Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran|Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran
[ 1 ] - Injury to skeletal muscle of mice following acute and sub-acute pregabalin exposure
Objective(s): Pregabalin (PGB) is a new antiepileptic drug that has received FDA approval for patient who suffers from central neuropathic pain, partial seizures, generalized anxiety disorder, fibromyalgia and sleep disorders. This study was undertaken to evaluate the possible adverse effects of PGB on the muscular system of mice. Materials and Methods: To evaluate the effect of PGB on skeletal...
[ 2 ] - Exploring the effect of intravenous lipid emulsion in acute methamphetamine toxicity
Objective(s): The increasing use of methamphetamine (METH) in the last decades has made it the second most abused drug. Advancs in the area of intravenous lipid emulsion (ILE) have led to its potential application in the treatment of poisoning. The present study aims to investigate the potential role of ILE as an antidote for acute METH poisoning. Materials and Methods: Two groups of six male r...
[ 3 ] - Therapeutic effects of HESA-A (a herbal-marine compound) in acute organophosphorus pesticide poisoning
Objective: Organophosphorus compounds (OPs) are common causes of poisonings. Atropine and oximes are pharmacological antidotes of OPs. However, because of their adverse effects and insufficient performance, several other compounds have been evaluated as adjuvant therapy. HESA-A is a herbal-marine drug that contains material from Carum carvi (Persian cumin), Penaeus latisculatus...