Firoozeh Alavian

Department of Basic Sciences, Farhangian University, Tehran, Iran

[ 1 ] - GABAB receptors within the central nucleus of amygdala may involve in the morphine-induced incentive tolerance in female rats

Objective(s): Central nucleus of amygdala (CeA) is the most important region for morphine-induced reward, and GABAergic system plays an important role on morphine reinforcement. The influence of CeA administration of GABAB receptor agonist and antagonist on the expression and acquisition of morphine-induced incentive tolerance using conditioned place preference (CPP) paradigm was investigated i...

[ 2 ] - Effects of preconditioning with intermittent normobaric hyperoxia on TNFR1 and TNFR2 expression in the rat brain

Introduction: Recent studies have shown that intermittent normobaric hyperoxia (HO) protects the rat brain from ischemia reperfusion injury. However, the exact mechanism of this kind of protection in vivo is not known. In this study, the effect of HO on expression of TNFR1 and TNFR2 in a stroke model was investigated. Methods: In this experimental study, rats were divided into 4 groups: no...

[ 3 ] - Intervention of the Gamma-Aminobutyric Acid Type B Receptors of the Amygdala Central Nucleus on the Sensitivity of the Morphine-Induced Conditionally Preferred Location in Wistar Female Rats

Background: The amygdala is one of the nerve centers involved in drug reward. It is suggested that the central nucleus of the amygdala (CeA) is involved in morphine dependency. The CeA gamma-aminobutyric acid-ergic (GABAergic) system is a mediator of morphine rewarding effects. In this research, the effects of stimulation or inhibition of CeA GABA type B (GABAB) receptors on sensitization acqui...

[ 4 ] - Effects of central amygdala GABA-B on expression of morphine-induced sensitivity in female rats

Introduction: Dependence on morphine and its complications are considered as a major health problem in the world; however, efforts to overcome this problem have failed due to the severity of drug dependence. Amygdala core nucleus (CeA) is one of the most important areas affecting the effects of morphine rewards. The GABAergic system in this nucleus; especially the GABAB receptors plays an impor...