Hamideh Mahmoodzadeh Hosseini

Applied Microbiology Research Center, System Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran

[ 1 ] - Immunogenicity of chimeric MUC1-HER2 vaccine against breast cancer in mice

Objective(s): Breast cancer is one of the most common cancers in the world and is on the increase. MUC1 and HER2 as tumor-associated antigens (TAAs) are abnormally expressed to some extent in 75–80% of breast cancers.  In our present research, a novel chimeric MUC1-HER2 (HM) protein was designed and used to study whether an immune response can be generated against these TAAs. In vitro analysis ...

[ 2 ] - The role of exosomes contents on genetic and epigenetic alterations of recipient cancer cells

Exosomes, as a mediator of cell-to-cell transfer of genetic information, act an important role in intercommunication between tumor cells and their niche including fibroblasts, endothelial cells, adipocytes and monocytes. Several studies have shown that tumor cells can influence their neighboring cells by releasing exosomes. These exosomes provide signaling cues for stimulation, activation, prol...

[ 3 ] - Evaluation of Inhibitory Effect of Three Phenolic Compounds; Linalool, Menthol and Eugenol on the Yeasts as Food Spoiling Agents

Aims: Although the use of yeasts as starters is common in the food industry, it can lead to product corruption and poor quality of food in some cases. Current study was assessed the anti-yeast impacts of three phenolic compounds; linalool, menthol and eugenol against 7 yeast species contaminating food products (Candida albicans, Candida kefir, Candida famata, Rhodotorula glutnis, Kluyveromyces ...

[ 4 ] - Determination of PCR-ELISA Diagnostic Value in Comparison With Classical Methods and PCR to Detect Resistance to Methacillin

Background and Aims: High prevalence of Methicillin Resistant Staphylococcus Aureus isolates (MRSA) as well as the multi-drug resistance in this bacterium causes difficulties in the treatment of infections due to these bacteria. Hence, detection of MRSA isolates by rapid and accurate methods is necessary. PCR-ELISA is an accurate and molecular technique that is used for the detection of several...

[ 5 ] - Clostridium Perfringens Toxin Types Associated with Meat: Review in Iran

Food poisoning due to Clostridium perfringens (C. perfringens) is a major food health problem, particularly in terms of meat consumption. Due to human’s susceptibility to this pathogen, detection methods and prevention measures should be implemented to reduce its incidence. Several pathogenic strains of C. perfringens have been identified so far. One of the potential concerns about this bacteri...