Zohreh Zavvari Oskuye
Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
[ 1 ] - Protective effects of troxerutin on maternal high-fat diet-induced impairments of spatial memory and apelin in the male offspring
Objective(s): Maternal high-fat diet (HFD) is linked with metabolic and cognitive deficits in offspring. Neuroprotective effects of troxerutin, a natural bioflavonoid, have been reported recently. This study aimed to investigate the effects of troxerutin on spatial memory and serum and hippocampal apelin levels in the male offspring of HFD fed mothers.Materials and Methods: Three-week-old femal...
[ 2 ] - Troxerutin affects the male fertility in prepubertal type 1 diabetic male rats
Objective(s): Diabetes can gradually cause damage to the function and structure of male gonads. This survey was conducted to investigate the effect of troxerutin on hormonal changes, serum oxidative stress indices, and testicular function and structure in prepubertal diabetic rats.Materials and Methods: Fifty prepubertal (6 weeks old) male Wistar rats were divided into five groups including Con...
[ 3 ] - Administration of troxerutin improves testicular function and structure in type-1 diabetic adult rats by reduction of apoptosis
Objective: The glucose-reducing effects of troxerutin was previously proven. This study was conducted to evaluate troxerutin effect on testicular structure and spermatozoid parameters in type-1 diabetic adult male rats. Materials and Methods: Fifty male Wistar rats were randomly clas...
[ 4 ] - Effect of troxerutin on apelin-13, apelin receptors (APJ), and ovarian histological changes in the offspring of high-fat diet fed rats
Objective(s): Maternal high-fat diet (HFD) consumption has been linked to metabolic disorders and reproductive dysfunctions in offspring. Troxerutin (TRO) has anti-hyperlipidemic, anti-oxidant, and anti-inflammatory effects. This study examined the effects of TRO on apelin-13, its receptors mRNA and ovarian histological changes in the offspring of HFD fed rats. <...
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