Fatemeh Zare Mehrjerdie
Neurobiomedical Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
[ 1 ] - Sulfur dioxide reduces hippocampal cells death and improves learning and memory deficits in rat model of transient global ischemia/reperfusion
Objective(s): According to recent the findings, sulfur dioxide (SO2) is produced by the cardiovascular system, influencing some major biological processes. Based on previous research, SO2 exhibits antioxidant effects and inhibits apoptosis following cardiac ischemia/reperfusion. Therefore, the objective of the current study was to examine the neuroprotective impact of SO2 following global cereb...
[ 2 ] - اثر سالویجنین بر یادگیری و حافظه و میزان بیان ژن mRNA فاکتور رشد دهنده عصبی مشتق از مغز (BDNF ) در هیپوکمپ موش صحرایی نر آلزایمری شده
Introduction: Effects of many flavonoids have been studied on memory, learning and improvement of Alzheimer. Many flavonoids are effective in the improvement of Alzheimer. Since no study has been conducted on the effect of salvigenin on memory and learning, our aim was to examine the effect of this flavonoid. Methods: Intraperitoneal injection of D-galactose at a dose of 120 mg / kg was used f...
[ 3 ] - بررسی اثر کارواکرول بر فشارخون و تعداد سلول‌های خونی در رت‌های مسموم شده با سرب
مسمومیّت با سرب باعث به هم خوردن تعادل اکسیدان و آنتی‌اکسیدان‌ها می‌شود که می‌تواند عامل بسیاری از اثرات سمّی سرب بر ارگان‌های مختلف، به‌ویژه سیستم قلبی عروقی باشد. از سویی کارواکرول که از ترکیب‌های اصلی گیاه آویشن است دارای خواص متنوعی ازجمله خاصیت آنتی‌اکسیدانی می‌باشد. هدف اصلی این مطالعه بررسی اثر کارواکرول بر فشار خون و برخی از پارامترهای خونی در رت‌های مسموم شده با سرب بود. در این مطالعه تع...
[ 4 ] - Effect of berberine chloride on caspase-3 dependent apoptosis and antioxidant capacity in the hippocampus of the chronic cerebral hypoperfusion rat model
Objective(s): The main goal of the current research was to examine the effects of Berberine (BBR) on apoptotic signaling and hippocampal oxidative stress induced by common carotid artery occlusion. Materials and Methods: Chronic cerebral hypoperfusion (CCH) model was created by occluding the two common carotid arteries (two-vessel occlusion [2VO]) permanently. BBR (50 and 100 mg/kg/daily) was i...
[ 5 ] - Effect of myricetin on the gene expressions of NOX3, TGF-β1, prestin, and HSP-70 and anti-oxidant activity in the cochlea of noise-exposed rats
Objective(s): Noise-induced hearing loss is one of the most common occupational diseases in industrialized countries and can be affected by various environmental and genetic factors. This study was designed to examine the effect of myricetin in preventing this disorder.Materials and Methods: Twenty-one Wistar rats were randomly divided i...
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