Leila Mehdizadeh Fanid
Cognitive Neuroscience, Department of Biology, University of Tabriz, 29 Bahman Bolvard, Tabriz, Iran.
[ 1 ] - The Survey of DBH Gene Polymorphism Rs5320 in Children with Attention Deficit Hyperactivity Disorder (ADHD)
Background Attention deficit hyperactivity disorder (ADHD) is a common behavioral disorder that affects 8-12% of school-age children. Several environmental and genetic factors play a role in the etiology of this disease. One of the genetic factors involved is dopamine beta-hydroxylase (DBH) gene, which plays an essential role in catecholamine synthesis by converting dopamine into norepinephrine...
[ 2 ] - Evaluating Sleep Disorders amongst Children with Attention Deficit/ Hyperactivity Disorder (ADHD)
Background: The attention deficit/ hyperactivity disorder (ADHD) is one of the most compromising mental disorders of childhood and adolescence. Subsequently, different studies in recent years were conducted on the relationship between sleep disturbances and ADHD in children. About 30% of children and 60% to 80% of adults with ADHD develop sleep disorders, which may result in cognitive and behav...
[ 3 ] - Study of Polymorphism of the DRD2 Gene (-141C Ins/Del, rs1799732) with Attention Deficit Hyperactivity Disorder a Population Sample of Children in Iranian-Azeri
BackgroundAttention deficit hyperactivity disorder (ADHD), is a multifactorial disorder and converging evidence has implicated abnormalities of dopamine neurotransmission. The aim of this study was to examine the association of -141 polymorphisms in DRD2 gene with ADHA among Iranian-Azeri population.Materials and Methods A case–control association study included 153 patients with attention defi...
[ 4 ] - An Association Analysis of Reelin Gene (RELN) Exon 22 (G/C), Rs.362691, Polymorphism with Autism Spectrum Disorder among Iranian-Azeri Population
Background Autism spectrum disorder (ASD) is a intricate childhood neuropsychiatric disorder that is described by deficits in communication of verbal and non-verbal, reciprocal social interactions, stereotypic behaviors, interests, and activities. The studies of post-mortem neuro-anatomical anomalies have indicated that migration alterations could occur early during development (first trimester...
[ 5 ] - The Association of DRD2 Gene TaqI Polymorphism with Attention Deficit Hyperactivity Disorder a Population Sample of Iranian Azeri-children
Background Attention deficit hyperactivity disorder (ADHD) is a multi-factorial disorder that has defined by hyperactivity, impulsivity and attention deficits. Various neurotransmitters such as dopamine can play a role in its pathophysiology. The aim of this study was to examine the association of two common single nucleotide polymorphisms in DRD2 gene, Taq I A (T/C) and Taq I B (G/A), with ADH...
[ 6 ] - Association between Common Single- nucleotide Polymorphism of Reelin Gene, rs736707 (C/T) with Autism Spectrum Disorder in Iranian-Azeri Patients
Introduction Reelin gene (RELN) codes a large extracellular matrix glycoprotein with serine protease activity and is implicated in the modulation of neuronal signaling, synaptic transmission and plasticity. The reelin plays a fundamental and pivotal role in the development of laminar structures and may be one of the loci contributing to the positive linkage between chromosome 7q and autistic di...
[ 7 ] - بررسی ارتباط پلی مورفیسمی های تک نوکلئوتیدی ( اگزون 22 ، ,rs362691 C>G و اینترون 59 ، rs736707 C>T ) ژنReelin با ناهنجاری طیف اوتیسم در کودکان مبتلای آذری در شمالغرب ایران
اختلاف طیف اتیسم (ASD) اختلال عصبی پیچیده دوران کودکی است که توسط نقص در ارتباطات کلامی و غیر کلامی، تعاملات اجتماعی متقابل، رفتارهای کلیشه ای، علایق و فعالیتها توصیف شده است. در طول رشد مغز جنینی Reelin سیگنالی را برای مهاجرت مناسب نورون های جدید حاصل از تقسیم میتوزی فراهم می کند. از آنجایی که ژن Reelin نقش بسیار مهمی در این فرآیند مهاجرتی دارد بنابراین، این ژن به عنوان یک ژن کاندید بالقوه ...
[ 8 ] - Evaluation of the Association of Htr2a Gene Rs6313 Polymorphism with Heroin Dependence in a Sample from Northwest Iran
Introduction: Heroin dependence is a chronic relapsing disorder caused by a combination of genetic, epigenetic, and environmental factors. The genetic contribution in the vulnerability to heroin dependence is 40%-60%. Alterations in dopamine transport in the CNS are implicated in drug and alcohol dependence, and according to linkage studies, the HTR2A rs6313 single nucleotide polymorphism plays...
[ 9 ] - Effects of Repeated Transcranial Magnetic Stimulation on Cognitive Functions of Police Personnel with Post-Traumatic Stress
Aims: The present study was conducted with the aim of investigating the effects of repeated magnetic brain stimulation on cognitive functions of police personnel with post-traumatic stress disorder (PTSD). This research was applied and semi-experimental with a pre-test-post-test research design with a control group. Materials and Methods: The statistical population included Naja police officer...