The Effect of Core Surface Tension on Roughness of Film - Coated Tablets

Authors

  • H Orafai
  • S Honary
Abstract:

The arithmetic mean roughness, Ra, values were determined by scanning electron microscopic technique of different core models (furazolidone, nitrofurantoin and acetyl salicylic acid), coated by HPMC film forming solution containing 10 wt% of various molecular weight PEGs. The results showed that both plasticizer molecular weight and core surface free energy could have a significant influence on Ra.

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Journal title

volume Volume 2  issue Number 1

pages  65- 66

publication date 2010-11-20

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