The Effect of Concurrent Training and Ginkgobiloba Supplement Eight Week on BDNF in Depressed Elderly

Introduction: The purpose of the current study was to examine the effect of concurrent training weeks eight and Gingkobiloba supplement on BDNF in depressed men elderly. Materials and Methods: Forty depressed men elderly were randomly divided into four groups (n = 10) in concurrent training, Gingkobiloba supplemental, concurrent training with Gingkobiloba supplemental and control. In the pre-test phase, blood samples were taken from the subjects in Noor laboratory, and then in the concurrent training group, the participants were trained for eight weeks and 3 sessions per week. In the Ginkgobiloba supplement group, the subjects were given 80 mg daily for eight weeks. In the concurrent training group with the Ginkgobiloba supplment, the subjects performed the concurrent training for 8 weeks, 3 times a week, and during the same period, they received 80 mg daily. Blood samples were taken again 24 hours after the last training session. The data analyzed with paired t-test, univariate analysis of covariance, and Bonferroni post hoc test. Results: The results showed that eight weeks of concurrent training, Ginkgobiloba supplement and combination of concurrent training with Ginkgobiloba supplement significantly increased BDNF in depressed older men (P <0.05). Other results showed an increase in the brain-derived neurotrophic factor of the concurrent training group with Ginkgobiloba supplement (84.78) compared with concurrent training (74.37) and Ginkgobiloba consumption (72.20) alone. Conclusion: Overall, the results suggest that professionals working with the elderly may be able to use a combination of concurrent training with Ginkgobiloba supplement to improve brain function.