Tannic acid: A Green Catalyst for the Eco-friendly Synthesis of 2,3-dihydroquinazolin-4(1H)-ones under Solvent Free Conditions
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Abstract:
A new, facile, cost effective, and eco-friendly protocol is reported for the synthesis of 2,3-dihydroquinazoline-4-(1H)-ones exploring tannic acid as a novel, inexpensive, andbiodegradable catalyst. A variety of dihydroquinazolins were prepared from aromatic aldehydesand anthranilamide using catalytic amount of tannic acid under solvent free conditions.Operational simplicity, high yield, and high atom-economy are the important features of thisprotocol.
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Journal title
volume 11 issue 4
pages 38- 45
publication date 2017-12-01
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