Synthesis of imidazo[2,1-b]thiazole-3-carboxylate through the reaction of thiohydantoins and ethylbromopyruvate

Authors

  • Mahboobeh Kiamarsi Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
  • Marzieh Jamali Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
  • Nasimeh Zarei Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
  • Pegah Mohagheghzadeh Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
Abstract:

Imidazo[2,1-b]thiazoles are obtaind in excellent yields from the addition reaction between thiohydantoin and ethylbromopyruvate.  These imidazo[2,1-b]thiazoles in the presence of p-TSA in boiling toluene refluxed for 2.5 hours led to imidazo[2,1-b]thiazole-3-carboxylates in elimination reactions

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Journal title

volume 1  issue 4

pages  11- 14

publication date 2011-05-01

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