Preparation of imidazo[2,1-b]thiazole-3-carboxylate by the condensation of thiohydantoins and ethylbromopyruvate

Authors

Marzieh Jamali Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran, [email protected], [email protected]

Nasimeh Zarei Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran, [email protected], [email protected]

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Synthesis of imidazo[2,1-b]thiazole-3-carboxylate through the reaction of thiohydantoins and ethylbromopyruvate

Imidazo[2,1-b]thiazoles are obtaind in excellent yields from the addition reaction between thiohydantoin and ethylbromopyruvate. These imidazo[2,1-b]thiazoles in the presence of p-TSA in boiling toluene refluxed for 2.5 hours led to imidazo[2,1-b]thiazole-3-carboxylates in elimination reactions

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reaction of thiohydantoins and ethylbromopyruvate for Synthesis of imidazo[2,1-b]thiazole 3-carboxylate

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synthesis of imidazo[2,1-b]thiazole-3-carboxylate through the reaction of thiohydantoins and ethylbromopyruvate

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Journal title

International Journal of Heterocyclic Chemistry

volume 6 issue 2

pages 9- 13

publication date 2016-11-01

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