P-11: Varicocele Improved Semen Quality and Chromatin Integrity in Normozoospermic and Non-Normozoospermic Varicocele Individual

Background: Varicocele is related with poor semen quality and sperm chromatin integrity which possibility decreases the spontaneous pregnancy potential. Some of the varicocele individuals have normal semen parameters with failed pregnancy. It is also one of the most controversial issues in the field ofinfertility, especially regarding why, when and for whom varicocelectomy should be implemented. It is unclear that whether varicocelectomy is beneficial for varicocele individuals with normal sperm parameter. Therefore, we aimed to compare spontaneous pregnancy rate in normozoospermic and non-normozoospermic varicocele individual undergoing varicocelectomy. Materials and Methods: Varicocele individual with grade II or III referred in Isfahan fertility and infertility divided tonormozoospermic group (n=81) and non-normozoospermic (n=64) groupsaccordingly World Health Organization guideline 2010. Cumulative spontaneous pregnancyafter varicocelectomy followed up during 12 month after varicocelectomy. Results: Spontaneous pregnancy achievedup to 50% in normozoospermic group and 45 % in non-normozoospermic group. Conclusion: Our study revealed that varicocelectomy has beneficial effect on normozoospermic and non-normozoospermic individual to achieve spontaneous pregnancy.