O24: Human Neural Stem/Progenitor Cells Derived from Epileptic Human Brain in a Self-Assembling Peptide Nanoscaffold Improve Traumatic Brain Injury in Rats

Authors

  • Borhani-Haghighi, Maryam Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran
  • Ghasemi, Sepideh Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran
  • Gorji, Ali a. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran. b. Department of Neuroscience, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. c. Department of Neurosurgery, Westfälische Wilhelms-Universität Münster, Münster, Germany. d. Department of Neurology, Westfälische Wilhelms-Universität Münster, Münster, Germany. e. Epilepsy Research Center, Westfälische Wilhelms-Universität Münster, Robert-Koch-Strasse 45, 48149 Münster, Germany
  • Hosseini Ravandi, Hassan Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran
  • Jahanbazi Jahan-Abad, Ali a. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran. b. Department of Clinical Biochemistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Khaleghi Ghadiri, Maryam Department of Neurosurgery, Westfälische Wilhelms-Universität Münster, Münster, Germany
  • Sahab Negah, Sajad a. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran. b. Department of Neuroscience, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  • Stummer, Walter Department of Neurosurgery, Westfälische Wilhelms-Universität Münster, Münster, Germany
Abstract:

This article doesn't have abstract

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

O13: Human Neural Stem/Progenitor Cells Derived from Epileptic Human Brain in A Self-Assembling Peptide Nanoscaffold Attenuates Neuroinlammation in Traumatic Brain Injury in Rats

Traumatic brain injury (TBI) is a disruption in the brain functions following a head trauma. Cell therapy may provide a promising treatment for TBI. Human neural stem cells cultured in self-assembling peptide scaffolds have been proposed as a potential novel method for cell replacement treatment after TBI. In the present study, we accessed the effects of human neural stem/progenitor cells (hNS/...

full text

O14: Application of Neural Stem Cells Derived from Human Meningioma in Traumatic Brain Injury

Traumatic brain injury is considered as one of the main causes of morbidity and mortality worldwide. Apart from primary mechanical injury, Secondary injuries due to inflammation and apoptosis result in great neuronal damage. Current treatments are not able to regenerate the damaged part and prevent future sequels. Using human stem cells with self-assembling scaffolds may be promising in treatme...

full text

P 104: Effects of Human Neural Stem Cells in Cure Neuroinflammation of Traumatic Brain Injury

Traumatic brain injury (TBI) is defined as an external mechanical injury to the brain. Neuroinflammation plays a vital role in the pathophysiology of TBI. Microglia and astrocytes play a central role in the initiation and regulation of inflammation. Numerous pro-inflammatory mediators including cytokines, chemokines, reactive oxygen species (ROS) and nitric oxide (NO) released by microglia. In ...

full text

O 26: Treatment of Traumatic Brain Injury in Adult Rats with Injection of Human Epileptic Neural Stem Cells and Nano-Scaffold

Traumatic brain injury (TBI) is described by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. The use of human stem cells and self-assembling peptide scaffolds suggest huge potential for application in the treatment of TBI. In the present study, we surveyed the beneficial effec...

full text

P91: Auto Graft Transplantation of Adult Human Neural Stem Cells in Treatment of Traumatic Brain Injury as a Hypothesis

Traumatic brain injury (TBI) leading to 5 million deaths annually is 1 of the 5 major causes of morbidity and mortality worldwide. In Iran, accidents are the main cause of death in youth as well as a dominant factor in reducing quality of life. In developing countries TBI incidence as one of the worst consequences of these accidents is growing due to wide use of motor-vehicles. Therapeutic stra...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 6  issue 3

pages  24- 24

publication date 2018-07

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

No Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023