Influence of pomegranate juice on sperm parameters and fertility in mice

Introduction: Sperm fertilization depends on a number of factors such as sperm count, motility and morphology. A variety of factors, including free radicals, may disturb the sperm characteristics. Elements such as vitamins C & E and polyphenols have anti-oxidental effects. Since sperms are weak in overcoming free radicals the aim of this study was to determine the effect of (PJ) on sperm count, morphology, motility and fertility in mice. Methods: In an experimental study, 20 male mice were studied with regard to their sperm parameters and fertility potential. Sperms were categorized into three groups with respect to their motility including progressive, non-progressive, immotile. Mice were divided into control group (n=10) and experimental group (n=10), randomly. The experimental group received 20% pomegranate juice for 1 month and one generation from each group was selected. By means of SPSS, Mann-Whitney test was used to compare the two groups. Results: The results showed that pomegranate juice consumption increased sperm count in cases (49.7±13.6) companed to control group (34.2±15.1). The difference was statistically significant (P=0.014). The rate of non progressive motility in case group was decreased when compared with control group (P=0.007). In addition, the normal morphology of cases improved significantly (P=0.001). The rate of fertility increased from 5.5±3.3 to 10.0±1.3 in case mice (P=0.007). Conclusion: Pomegranate juice is able to improve the quality of sperm parameters, as well as fertility potential in mice. Probably, intake of this antioxidant by infertile men improves the quality of their sperm parameters.