Effects of zinc oxide nanoparticles on antioxidant status, serum enzymes activities, biochemical parameters and performance in broiler chickens

This research was conducted to investigate the effect of zinc oxide Nanoparticles (nano-ZnO) in diets on the performance, antioxidant status, enzymes activity and some hematological parameters of broiler chickens. A total of 600 one–day-old male Ross 308 broilers were allocated to four treatment groups with five replications of 30 each from day 1 to 42 day of age. The birds were continuously diets supplemented with 0 (control), 10, 20 and 40 mg/kg of nano-ZnO as four experimental treatments. Average daily gain (ADG), Average daily feed intake (ADFI) and feed conversion ratio (FCR) were measured from 1 to 42 d of age. Triglyceride, high density lipoprotein (HDL), activity of alkaline phosphatase (ALP), Aspartate transferase (AST), alanine transferase (ALT), creatine kinase (CK), Total antioxidant capacity (T-AOC),‌ superoxide dismutase (SOD), Malondialdehyde (MDA), and Glutathione peroxidase (GPx), were measured at 42 d of age. Broilers receiving 10 mg/kg nano-ZnO had significantly (P0.05) affected by treatments. In conclusion, the results of this study showed the inclusion of 20 mg/kg nano-ZnO improved the growth performance and antioxidant status in broilers.