Effect of noise stress on in-vivo fertilization capacity of male rats and subsequent off spring quality

Objective: The present experimental study was designed to investigate the elucidative effect of 50 days of noise stress on fertilization capacity of rat and subsequent offspring quality. Material and Methods: Two groups of 10 male rats were placed in two control and experimental groups for 50 days. In the experimental group, 90-120 dB sound intensity and frequency of 300-350 Hz of the device (daily at 7 pm to 7 am) was broadcasting. After this period, the male rats of both groups were exposed to the same breed female rats in a cage than 1:2 for mating. Every morning for seven days the female rats with positive vaginal plaque were separated and after 19 days were killed by cervical dislocation method then uterus and ovaries were examined for the number of corpora lutea, dead and live fetuses, embryo resorption, implantation sites and fetus weight. Results: Statistical studies showed that the noise stress significantly reduced the total number of embryos and alive embryos in the test group (p<0.05).As the number of dead embryos and embryos that are absorbed significantly are increased in rats which exposed to noise stress (p<0.05). Conclusion: Results of this study have important implications for families attempting pregnancy. Stress pursuant to life events may have a negative impact on in vivo fertilization capacity of male rats and subsequent offspringquality.