Derivation and validation of a sensitivity formula for knife-edge slit gamma camera: A theoretical and Monte Carlo simulation study

Authors

  • Elisa Fiorina National Institute of Nuclear Physics, Section of Torino, Torino, Italy|Clinical Department, Fondazione CNAO, Pavia, Italy
  • Etesam Malekzadeh Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
  • Faraz Kalantari Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
  • Hossein Rajabi Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Abstract:

Introduction: Gamma cameras are proposed for online range verification and treatment monitoring in proton therapy.  An Analytical formula was derived and validated for sensitivity of a slit collimator based on the photon fluence concept. Methods: Fluence formulation was generalized for photons distribution function and solved for high-energy point sources. The effect of the collimator slit size and source off-axis position on the sensitivity of the collimator were included in the formula. Results: The analytically calculated sensitivities of the slit collimator were in good agreement with Monte Carlo results according to the Bland-Altman agreement test and Pearson correlation (r =0.998) statistical analysis with   . The mean relative error between calculated sensitivities with the derived formula and Monte Carlo was up to 0.8%. Moreover, we found that under certain conditions, the established formula is converted to the Anger equation for the pinhole collimator. Conclusion: The analytical formula developed in this research can estimate the slit collimator sensitivity with an acceptable accuracy. The derived closed-form sensitivity formula can be applied in KE collimator design and optimization studies.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

construction and validation of a computerized adaptive translation test (a receptive based study)

آزمون انطباقی رایانه ای (cat) روشی نوین برای سنجش سطح علمی دانش آموزان می باشد. در حقیقت آزمون های رایانه ای با سرعت بالایی به سمت و سوی جایگزین عملی برای آزمون های کاغذی می روند (کینگزبری، هاوسر، 1993). مقاله حاضر به دنبال آزمون انطباقی رایانه ای برای ترجمه می باشد. بدین منظور دو پرسشنامه مشتمل بر 55 تست ترجمه میان 102 آزمودنی و 10 مدرس زبان انگلیسی پخش گردید. پرسشنامه اول میان 102 دانشجوی س...

a study on rate making and required reserves determination in reinsurance market: a simulation

reinsurance is widely recognized as an important instrument in the capital management of an insurance company as well as its risk management tool. this thesis is intended to determine premium rates for different types of reinsurance policies. also, given the fact that the reinsurance coverage of every company depends upon its reserves, so different types of reserves and the method of their calc...

Evaluation of the Effects of Inhomogeneities on Dose Profiles Using Polymer Gel Dosimeter and Monte Carlo Simulation in Gamma Knife

Introduction Polymer gel dosimeters offer a practical solution to 3D dose verification for conventional radiotherapy as well as intensity-modulated and stereotactic radiotherapy. In this study, EGSnrc calculated and PAGAT polymer gel dosimeter measured dose profiles from single shot irradiation with 18 mm collimator of Gamma Knife in homogeneous and inhomogeneous phantoms were compared with eac...

full text

the study of practical and theoretical foundation of credit risk and its coverage

پس از بررسی هر کدام از فاکتورهای نوع صنعت, نوع ضمانت نامه, نرخ بهره , نرخ تورم, ریسک اعتباری کشورها, کارمزد, ریکاوری, gdp, پوشش و وثیقه بر ریسک اعتباری صندوق ضمانت صادرات ایران مشخص گردید که همه فاکتورها به استثنای ریسک اعتباری کشورها و کارمزد بقیه فاکتورها رابطه معناداری با ریسک اعتباری دارند در ضمن نرخ بهره , نرخ تورم, ریکاوری, و نوع صنعت و ریسک کشورها اثر عکس روی ریسک اعتباری داردو پوشش, وثی...

15 صفحه اول

a study on thermodynamic models for simulation of 1,3 butadiene purification columns

attempts have been made to study the thermodynamic behavior of 1,3 butadiene purification columns with the aim of retrofitting those columns to more energy efficient separation schemes. 1,3 butadiene is purified in two columns in series through being separated from methyl acetylene and 1,2 butadiene in the first and second column respectively. comparisons have been made among different therm...

Evaluation of Organ Specific peripheral dose for Gamma knife 4C based on Monte Carlo

Introduction: Stereotactic Gamma Knife radiosurgery has been widely used for treating brain tumors. The scattered radiation outside of treatment field (peripheral dose) can induce the secondary cancer to specific organ. This paper investigated the absorbed dose to eyes, thyroid, heart, lung, breast and colon using a Monte Carlo technique for Mird phantom. We also study the ef...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 29  issue 2

pages  86- 92

publication date 2021-07-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023