Comparison of the efficacy of topical 85% formic acid versus a combination of topical salicylic acid and lactic acid in the treatment of warts: A randomized, triple-blind, controlled trial
Authors
Abstract:
Background: Wart is a common skin disease that can occur at any age. While they are usually benign and self-limited, they can become irritating and cosmetically disabling to patients. The objective of this study is to compare the effectiveness of a topical 85% formic acid preparation with a combination of topical salicylic acid and lactic acid.Methods: We enrolled 66 patients, 7-60 years of age, in this triple-blind study. Patients were randomly divided into 2 groups: group 1 received a topical 85% formic acid solution and group 2 received DuoFilm (topical 16.7% salicylic acid + 16.7% lactic acid). The duration of treatment was a maximum of 4 weeks and we followed the patients every two weeks.Results: In group 1, 74.1% of the warts completely healed and 3.5% partially healed. In group 2 complete healing occurred in 40.8% and partial healing in 26.8% of the warts (P<0.001). Statistical analysis showed a significant difference in the favor of formic acid on the hands (P<0.001) but we did not observe a better effect for the feet. The time to complete healing was less for the majority of patients in the formic acid group (1 week versus 4 weeks). There were minimal adverse effects in each group, none that necessitated cessation of treatment.Conclusion: Topical formic acid had a higher cure rate for warts compared with a conventional preparation that consisted of both topical salicylic acid and lactic acid. This effect was particularly noted on the hands. This topical remedy could be regarded as an alternative to conventional treatments in the management of warts.
similar resources
a double-blind, randomized trial on topical formic acid puncture technique in the treatment of common warts
background: viral warts are a common problem especially in young people. they are important as they are transmittable and cause social embarrassment. though there are several treatments for viral warts, none offer a fast, simple, complete cure by itself. a simple and inexpensive way of treatment would be outstanding, especially in developing countries. we aimed to determine the efficacy and saf...
full texthistological evaluation of the effect of three medicaments; trichloracetic acid, formocresol and mineral trioxide aggregate on pulpotomized teeth of dogs
چکیده ندارد.
15 صفحه اولLiquid nitrogen cryotherapy versus 70% trichloroacetic acid in the treatment of anogenital warts: A randomized controlled trial
Background: Cryotherapy is one of the most common and effective treatments of anogenital warts, and trichloroacetic acid is one of the methods commonly used. The aim of this study was to compare the effect of cryotherapy and trichloroacetic acid in the treatment of anogenital warts.Methods: This randomized clinical trial was conducted on patients with anogenital warts. The patients were divided...
full textMy Resources
Journal title
volume 19 issue 1
pages 14- 5
publication date 2016-01-01
By following a journal you will be notified via email when a new issue of this journal is published.
Keywords
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023