Betamethasone Can Significantly Decrease Level of Striatal Glutamate in Animal Model of Parkinson's Disease
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Abstract:
In the present study, the effect of steroidal anti-inflammatory drug betamethasone (0.12, 0.24 mg/kg, i.p. acutely) on striatal glutamate level in Parkinsonian rats was studied using the microdialysis technique. Our results showed significant differences (p
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betamethasone can significantly decrease level of striatal glutamate in animal model of parkinson's disease
in the present study, the effect of steroidal anti-inflammatory drug betamethasone (0.12, 0.24 mg/kg, i.p. acutely) on striatal glutamate level in parkinsonian rats was studied using the microdialysis technique. our results showed significant differences (p<0.05) in the level of striatal glutamate between treated and non-treated damaged rats.
full textA study on striatal local electrical potential changes in an animal model of Parkinson's disease
Parkinson’s disease (PD) is a neurodegenerative disorder that does not develop spontaneously in some animal species. PD can be induced experimentally in some laboratory animals including mouse, rat and horse. Globus pallidus (GP) and substantia nigra pars compacta (SNc) are damaged in patients with PD. The hallmark of PD is a progressive impaired control of movement, an alteration of autonomic ...
full textA study on striatal local electrical potential changes in an animal model of Parkinson's disease
Parkinson’s disease (PD) is a neurodegenerative disorder that does not develop spontaneously in some animal species. PD can be induced experimentally in some laboratory animals including mouse, rat and horse. Globus pallidus (GP) and substantia nigra pars compacta (SNc) are damaged in patients with PD. The hallmark of PD is a progressive impaired control of movement, an alteration of autonomic ...
full textEffect of Dexamethasone on Striatal Neurotransmissions in the Rats Subjected to Parkinson’s Disease Animal Model
Objective(s) The aim of this study was to evaluate the effects of dexamethasone on striatal dopaminergic, glutamatergic and gamma amino butyric acid (GABA) ergic neurotransmission in normal and parkinsonian rats. Materials and Methods Dexamethasone (0.15, 0.30, 0.60 and 0.8 mg/kg) was administered to normal or parkinsonian rats (i.p.) followed by the analysis of the striatal neurotransmitter...
full texteffect of dexamethasone on striatal neurotransmissions in the rats subjected to parkinson’s disease animal model
objective(s) the aim of this study was to evaluate the effects of dexamethasone on striatal dopaminergic, glutamatergic and gamma amino butyric acid (gaba) ergic neurotransmission in normal and parkinsonian rats. materials and methods dexamethasone (0.15, 0.30, 0.60 and 0.8 mg/kg) was administered to normal or parkinsonian rats (i.p.) followed by the analysis of the striatal neurotransmitters c...
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Journal title
volume Volume 7 issue Number 3
pages 229- 232
publication date 2010-11-20
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