Base Catalyzed Cyclization and Isomerization of 3-Propargylmercapto-1, 2,4-Triazine to Thiazolo [3,2-b][1,2,4]-Triazines
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Abstract:
Transformation of 3-propargylmercapto-6 methyl-1, 2,4-triazin- 5 (2H)- one (1; R=CH3) to 3,6- dimethyl-7H- thiazolo [3,2-b] [1, 2, 4] triazin -7- one (2) is performed under basic condition. The formation of (2) may be mainly due to the high reactivity of acetylenes towards nucleophiles and isomerization of the intermediate.
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Journal title
volume 11 issue 2
pages 8- 11
publication date 1992-12-01
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