An Efficient One-pot Synthesis of Dialkyl fumarates Mediated by inyltriphenylphosphonium Salt in the Intramolecular Wittig Reaction
Authors
Abstract:
An efficient three-component reaction of dialkyl acetylendicarboxylates and 2-Pyrrolidin in the presence of triphenylphosphine produces dialkyl 2-(2-Pyrrolidin-N-yl)-3-(triphenylphosphanylidene)succinate. These phosphoranes undergo mild intramolecular Wittig reaction to produce dialkyl (E)-2-(4,5-dihydro-3H-pyrrol-2-yl)fumarate in excellent yields.
similar resources
an efficient one-pot synthesis of dialkyl fumarates mediated by inyltriphenylphosphonium salt in the intramolecular wittig reaction
an efficient three-component reaction of dialkyl acetylendicarboxylates and 2-pyrrolidin in the presence of triphenylphosphine produces dialkyl 2-(2-pyrrolidin-n-yl)-3-(triphenylphosphanylidene)succinate. these phosphoranes undergo mild intramolecular wittig reaction to produce dialkyl (e)-2-(4,5-dihydro-3h-pyrrol-2-yl)fumarate in excellent yields.
full textAn Efficient Synthesis of 4H-chromene Derivatives by a One-pot, Three-component Reaction
A facile and efficient one-pot, multicomponent synthesis of 4H-chromenes is reported, through the reaction of arylglyoxalmonohydrates with 1,3-diketones and malononitrile in eTEMPthanol in the presence of L-proline as a catalyst.
full textA Facile One-Pot Synthesis of Functionalized N-Hydroxypyrrole Mediated by Vinyl-Triphenylphosphonium Salt
Protonation of the reactive intermediates generated in the raction between dalkyl acetylenedicarboxylates and triphenylphosphine by isonitrosoacetophenone leads to vinyltriphenylphosphonium salts, which undergo intramolecular Wittig reaction to produce dalkyl 4-phenyl-N-hydroxypyrrole-2,3-dicarboxylates in moderate yields.
full textNanocrystalline TiO2 as an efficient and reusable catalyst for the one-pot synthesis of polyhydroquinolien derivatives via Hantzsch reaction
An efficient synthesis of polyhydroquinoline derivatives was reported via four-component coupling reactions of aldehydes, 1,3-dicarbonyl ketones (dimedone or 1,3-cyclohexanedione), ethyl acetoacetate or methyl acetoacetate and ammonium acetate in the presence of a catalytic amount of nanocrystalline TiO2 under solvent free conditions. The reported method is mild, rapid and has the advantages su...
full textNanocrystalline TiO2 as an efficient and reusable catalyst for the one-pot synthesis of polyhydroquinolien derivatives via Hantzsch reaction
An efficient synthesis of polyhydroquinoline derivatives was reported via four-component coupling reactions of aldehydes, 1,3-dicarbonyl ketones (dimedone or 1,3-cyclohexanedione), ethyl acetoacetate or methyl acetoacetate and ammonium acetate in the presence of a catalytic amount of nanocrystalline TiO2 under solvent free conditions. The reported method is mild, rapid and has the advantages su...
full texta facile one-pot synthesis of functionalized n-hydroxypyrrole mediated by vinyl-triphenylphosphonium salt
protonation of the reactive intermediates generated in the raction between dalkyl acetylenedicarboxylates and triphenylphosphine by isonitrosoacetophenone leads to vinyltriphenylphosphonium salts, which undergo intramolecular wittig reaction to produce dalkyl 4-phenyl-n-hydroxypyrrole-2,3-dicarboxylates in moderate yields.
full textMy Resources
Journal title
volume 3 issue 1
pages 27- 30
publication date 2015-12-01
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023