Aluminum Phosphide Poisoning: A Case Series in North Iran
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Abstract:
Background: Aluminum phosphide (AlP) poisoning is one of the most life threatening emergencies. In this study, demographic characteristics, clinical profiles and outcomes of a series of patients presented with AlP poisoning in north Iran are described. Methods: The study was a retrospective descriptive medical chart review of AlP poisoned patients who were admitted to internal ward of Imam Khomeini hospital, Sari, Iran, from July 1st 2011 to July 1st 2012. Collected data included gender, age, intention of poisoning, amount of AlP ingested, clinical manifestations at admission, therapeutic interventions, laboratory tests and outcome. Results: During the one-year period, 8 patients which were all men with mean (SD) age of 40.5 (22.5) years were admitted with AlP (rice tablet) poisoning. The most common signs and symptoms at admission were nausea and vomiting (100%), metabolic acidosis (100%) and hemodynamic instability (87.5%). All cases were poisoned as a result of suicidal attempt leading to 5 (62.5.6%) deaths. Compared with the patients who survived, those who died had taken higher doses of AlP, developed hepatic dysfunction in higher rates and had severer metabolic acidosis. All patients were admitted to intensive care unit and received gastric washing with sodium bicarbonate, followed by activated charcoal therapy and intravenous calcium gluconate for decontamination purposes. The median (IQR) of length of hospital stay was 2 (1-4) days. Conclusion: AlP is a low-cost highly-toxic rodenticide. It is easily available and used as a toxic compound for suicide in the Asia region. There has been no effective antidote available for treatment of AlP poisoned patients; thus, symptomatic management should be taken into consideration as soon as possible.
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aluminum phosphide poisoning: a case series in north iran
background: aluminum phosphide (alp) poisoning is one of the most life threatening emergencies. in this study, demographic characteristics, clinical profiles and outcomes of a series of patients presented with alp poisoning in north iran are described. methods: the study was a retrospective descriptive medical chart review of alp poisoned patients who were admitted to internal ward of imam khom...
full textComment on "Aluminum Phosphide Poisoning: a Case Series in North Iran"
Dear Editor, I read with great interest the brief report entitled "Aluminum Phosphide Poisoning: A Case Series in North Iran" presented by Nosrati et al. and published recently in your journal (1). I have a question from authors and also a suggestion regarding aluminum phosphide (AlP) poisoning- related studies. I would like to ask authors how they validate the study results, since it is not...
full textAuthor Response to Comment on "Aluminum Phosphide Poisoning: A Case Series in North Iran"
Dear Editor; I wish to thank the authors for their careful comment (1), on our short report entitled “Aluminum Phosphide Poisoning: A Case Series in North Iran” (2). Unfortunately, as we were excited to display the findings of our series, some facts were missed from the methods of the article. The results presented in our series was collected from eight patients with definitive aluminum phosp...
full textAn interesting case of aluminum phosphide poisoning
Ingestion and inhalation of phosphine are 2 forms of toxicity and their clinical manifestation is extremely wide. A 22-year-old girl was admitted with complaints of nausea, vomiting and epigastric pain after eating lunch. She had a history of celiac disease. On arrival, she was alert and hemody...
full textA Case Report of Successful Treatment of Aluminum Phosphide Poisoning
Introduction: Aluminum phosphide is one of the most common causes of poisoning in the country. It liberates lethal phosphine gas when it comes in contact either with atmospheric moisture or with hydrochloric acid in the stomach. It mainly attacks the cardiovascular and respiratory systems. Eating even small amounts of this toxin can lead to death. This study reports a case of successful treatme...
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Journal title
volume 2 issue 3
pages 111- 113
publication date 2013-09-01
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