A green, efficient, and rapid procedure for the synthesis of pyrano[3,2-c] quinoline and pyrano[3,2-c]pyridone derivatives catalyzed by [BMIm]Cl

Authors

  • Aidin Mohammadi-Barkchai Department of Applied chemistry, Ardabil Branch, Islamic Azad University, Ardabil, zip code 56157, I.R. Iran.
  • Kurosh Rad-Moghadam Department of Chemistry, Faculty of Science, University of Guilan, Rasht, zip code 41335, I.R. Iran.
  • Seyyedeh Cobra Azimi Department of Chemistry, Faculty of Science, University of Guilan, Rasht, zip code 41335, I.R. Iran.
Abstract:

A highly practical and efficient preparation of pyrano[3,2-c]pyridone and pyrano[3,2-c]quinoline derivatives was developed via an ionic liquid mediated and promoted multi-component reaction of malononitrile, aldehyde, and 4-hydroxyquinolin-2(1H)-one or 4-hydroxy-6-methylpyridin-2(1H)-one. The combinatorial syntheses were achieved for the first time without applying extra activation energy at ambient temperature while making use of [BMIm]Cl as a catalyst solvent.

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Journal title

volume 3  issue 1

pages  15- 20

publication date 2013-03-01

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