A green and highly effective protocol for the synthesis of N,N′-alkylidene bisamides using saccharin-N-sulfonic acid

Authors

  • Abdolkarim Zare Department of Chemistry, Payame Noor University of Bushehr, Bushehr, Iran
  • Fatemeh Fakhraei Department of Chemistry, Payame Noor University, PO Box 19395-3697 Tehran, Iran
  • Manije Dianat Department of Chemistry, Payame Noor University, P.O. Box 19395‐3697 Tehran, Iran
  • Nasrin Pishahang Department of Chemistry, Payame Noor University, PO Box 19395-3697 Tehran, Iran
  • Roghayyeh Khanivar Department of Chemistry, Payame Noor University, PO Box 19395-3697 Tehran, Iran
  • Zahra Kordrostami Department of Chemistry, Payame Noor University, PO Box 19395-3697 Tehran, Iran
Abstract:

A green and highly effective solvent-free protocol has been reported for the synthesis of N,N′-alkylidene bisamides via the reaction of arylaldehydes (1 eq.) with primary amides (2 eq.) in the presence of saccharin-N-sulfonic acid (SaSA) as a solid-acid catalyst. The mentioned compounds have been obtained in high yields and short reaction times.

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Journal title

volume 8  issue 1

pages  58- 66

publication date 2020-01-01

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