گزارش یک مورد تغییرات دیسپلاستیک و بدخیمی های متعدد دربیمارمبتلا به اپیدرمودیسپلازیا وروسیفورمیس

Introduction: Epidermodysplasia verruciformis(EV) is a very rare, chronic and inherited disorder characterized by widespread and persistent HPV infection. EV Patients present with widespread, discrete or confluent lesions that clinically indistinguishable from plane warts , scaly hyper or hypopigmented macules closely resemble pityriasis versicolor, and thicker plaques may resemble seborrbeic keratosis. Susceptibility to the virus is inherited, usually autosomal recessive. The disease usually manifests in childhood and continue throughout the life. The most important complication is cutaneous changes of dysplasia and malignancy. Case Report: We report a 19 years old boy with clinical and histopathological findings compatible with EV and cutaneous changes of dysplasia and malignancy. Conclusion: We concluded that in patients with combination of plane warts, pityriasis versicolor-like lesions and reddish plaques, it may be considered EV, and it is recommended to evaluate cutaneous changes of dysplasia and malignancy.