تأثیر هشت هفته تمرین مقاومتی و مکمل زنجبیل بر سوپراکسید دیسموتاز (سرمی) بیماران دیابت نوع 2

Background and purpose: Metabolic disorders are amongst the major risk factors for health in the world. This study aimed at investigating the effect of eight weeks resistance training and ginger consumption on some antioxidant markers and oxidative stress in patients with type 2 diabetes. Materials and methods: In a double blind clinical trial with semi-experimental design, 44 patients with type 2 diabetes (mean height 169.92±7.20 cm, weight 82.41±6.34 kg, age 53.49±7.01 years, and body composition 28.57%±2.07 m2) were selected using purposive sampling. They were randomly divided into four groups: ginger rhizome, resistance training+ placebo, resistance training+ ginger rhizome, and placebo. The subjects in ginger rhizome group received that 1mg for eight weeks. Other patients attended a progressive resistance protocol with 65 to 80% 1RM for 8 weeks (three times a week). Blood samples were collected from antecubital vein before and 48 hr after the experiment. Superoxide dismutase indicator was measured by ELISA method. Data analysis was done applying independent t-test, repeated measure of ANOVA, and Tukey's Post Hoc Test. Results: Eight weeks of resistance training and ginger significantly increased superoxide dismutase indicator in all groups except in placebo group (p≥0.05). Conclusion: According to current findings, long-term consumption of ginger and resistance training could be of great benefit in changing antioxidant index in patients with type 2 diabetes.   (Clinical Trials Registry Number: IRCT20181205041856N1)