تأثیر عصاره بابونه بر پیشگیری از استوماتیت ناشی از شیمی درمانی در کودکان مبتلا به سرطان

Abstract Background and purpose: Ostomatitis or oral mucositis is common problem in patients undergoing chemotherapy that results in complications such as pain, infection, malaise and increased length of hospital stay. Oral hygiene and application of an appropriate mouthwash are only ways for prevention of these problems. The goal of this study was to assess the effect of Chamomile mouthwash to prevent ostomatitis in children undergoing chemotherapy. Materials and methods: In this quasi-experimental-double blinded study 52 children undergoing chemotherapy were randomly assigned in two study and control groups. Patients in the study group were taught to brush their teeth, troll a diluted solution of Chamomile mouthwash (30 drops in 20 ml water), for one minute, and then outpour it and do not eat anything for an hour, three times a day for 14 days. Patient's mouth was examined on days 7 and 14 and then their ostomatitis recorded according to WHO scale. Results: Result indicated that incidence of ostomatitis in study group after 7 days was 42.3% and in control group was 76.9% (P≤0.01). Conclusion: Chamomile can be used as a suitable mouthwash to prevent ostomatitis in children undergoing chemotherapy and leads to improving nutrition and satisfaction of children and parents.