بررسی وضعیت ویتامین D در مبتلایان به پرفشاری خون در مرکز بهداشتی درمانی آزادشهر یزد سال 1392

Introduction: Vitamin D deficiency has been known as one of the most important factors having effect on pathogenesis and progression of hypertension. The purpose of present study was to determine vitamin D status in patients with hypertension in Yazd. Methods: Fifty six patients(21 men and 35 women) aged 25-50 years who had profile in AZAD SHAHR health and treatment center of Yazd whose hypertension remeasured to diagnosis of indispensable hypertension (systolic blood pressure over 140 mmHg or diastolic blood pressure over 90 mmHg) participated in this cross-sectional study. Data were collected by blood sampling to measure serum 25 Hydroxyvitamin D, PTH, calcium, sodium, potassium, phosphorus and magnesium. Vitamin D deficiency was determined at the level of 25 Hydroxyvitamin D lower than 30 ng/ml. In this study sever deficiency of vitamin D deficiency defined as 25 Hydroxyvitamin D lower than 10 ng/ml, moderate deficiency defined as 25 Hydroxyvitamin D between 10-19.9 ng/ml and mild deficiency defined as 25 Hydroxyvitamin D between 20-29.9 ng/ml. Results: The results show that 19 of patients (33.9%) had sever deficiency, 16 had moderate (28.6%) and 7 had mild vitamin D deficiency (12.5%). Only 14 of participants had normal status (25%). All patients had normal serum PTH, calcium, sodium, potassium, phosphorus and magnesium. There wasn't any significant relationship between gender or age and vitamin D status. Conclusion: We observed a high frequency of vitamin D deficiency in hypertensive patients in this study. In addition, the effect of resolving vitamin D deficiency on blood pressure is recommended.