بررسی مقایسه ای آسیب های روان شناختی و رفتاری داروهای ضد صرع در بیماران مصروع

Authors

  • عسگری مبارکه, کریم
  • زارعی, حلیمه
Abstract:

Introduction & Objective: Patients suffering from epilepsy can experience a wide range of neuropsychological disorders such as impaired memory, attention and information process-ing. The aim of the present study was to evaluate and compare the performance of neuropsy-chological epileptic patients according to their pharmacotherapy. Materials & Methods: In this retrospective causal- comparative study, 90 patients with idio-pathic grand mal epilepsy in three groups of 30 subjects taking drug valproate acid, car-bamazepine and combination lamotrigine (with carbamazepine or valproate) were selected in Hamadan clinics in 2012. 30 cases of normal subjects with an age range of 15 to 55 years were included (control group). The four groups of subjects were matched in age and educa-tion and were evaluated according to continuous performance tests, Benton visual retention test, and Paced Auditory Serial Addition Test (PASAT). The data was analyzed by SPSS software and Manova, Scheffe, Tamhane tests. Results: The results show that the rate of PASAT in normal group was significantly higher than epilepsy group (P=0.01), but among the groups taking valproate acid, carbamazepine and combination lamotrigine (with carbamazepine or valproate) no significant difference was observed in the level of depression. In PASAT and Benton visual retention tests the results were similar. In continuous performance test n the scale of incorrect response the results were reversed and with regard to the correct response, the previous results were confirmed. On omission reply scale, the group which used combination lamotrigine and the normal group showed similar results, thus they were separated from the group using carbamazepine and valproate. On reaction time scale, patients taking carbamazepine significantly (P=0.01) differed from patients taking amotrigine and valproate and from the normal group. Conclusion: There are significant differences between the AEDs as valporate, carbamazepine and combination therapy in terms of their neuropsychological profiles.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

بررسی سلامت روان و شیوه های مقابله با استرس در خانواده بیماران مصروع مراجعه کننده به انجمن صرع ایران

سابقه و هدف: صرع از بیماری های بسیارشایع همه کشورهاست. حضور بیمار مصروع در خانواده، بازیابی و سازمان دهی مناسب نظم و مقررات و تلاش در جهت گسترش الگوهای تعاملی مناسب بین اعضا خانواده را الزامی می سازد. ارتقا سلامت روان و استفاده از شیوه های مقابله با استرس مناسب برای بیماران مصروع و خانواده های انها موثر و ضروری می باشد. روش بررسی: در این مطالعه توصیفی– همبستگی، 150 نفر از خانواده بیماران مصر...

full text

مقایسه تاثیر داروهای ضد روان پریشی تیپیک و الانزاپین بر قند خون ناشتای بیماران روانپزشکی

Background and purpose: Low extrapyramidal symptoms, weight gain, increased fasting blood sugar and cholestrole are some of the side effects of antipsychotic drugs that can be dangerous for patients. Atypical antipsychotics like olanzapine have little extrapyramidal side effects, but they may induce weight gain and increase FBS. Materials and Methods: In this simple randomized double blind...

full text

مقایسه ناگویی ‌هیجانی در بین بیماران مصروع تونیک- کلونیک، صرع میوکلونیک جوانان و افراد سالم

زمینه و هدف: صرع اختلال مزمن و طغیان عمل مغزی است که به علت تخلیه نابهنجار الکتریکی نورون­های مغز پیدا می­شود و مشکلاتی چون نوسانات خلقی، افسردگی و اضطراب برای بیماران بدنبال دارد. هدف از پژوهش حاضر مقایسه ناگویی ‌هیجانی در بیماران مصروع تونیک- کلونیک، صرع میوکلونیک جوانان و افراد سالم می‌باشد. روش­کار: مطالعه حاضر بر اساس طرح پس رویدادی (علی- مقایسه­ای)، با روش نمونه‏گیری در دسترس تنظیم شد. ج...

full text

اثربخشی درمان شناختی- رفتاری بر نگرش های ناکارآمد در بیماران مبتلا به صرع

Introduction: Epilepsy is a brain disorder that has neurobiological, cognitive, psychological, and social consequences for affected patients. The purpose of this research was to determine the efficacy of cognitive behavioral therapy(CBT) on modification of dysfunctional attitudes in patients with epilepsy. Methods: In the study, 20 epileptic patients were randomly assigned to two experimental...

full text

مقایسه اثربخشی داروهای ضد خارش در بیماران نارسایی مزمن کلیه

Background: Pruritus is one of the most common problems in patients suffering chronic renal failure. Twenty five - 35% of predialysis patients and 60-80% of patients during dialysis complain pruritus. The exact pathophysiology of pruritus is unknown however, some possible interactive factors include: histamine release from mast cells and basophiles, uremic skin, cutaneous mast cells proliferati...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 21  issue 2

pages  137- 144

publication date 2014-09

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

No Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023